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A Rare Case of Idiopathic Granulomatous Mastitis in a Nulliparous Woman with Hyperprolactinemia

Idiopathic granulomatous mastitis (IGM) is a rare, benign, and chronic inflammatory condition of the breast. Women of child-bearing age with a recent history of pregnancy and lactation are usually affected, and clinical picture mimics inflammatory breast cancer or breast abscess. The etiology is not...

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Detalles Bibliográficos
Autores principales: Agrawal, Ankit, Pabolu, Sangeetha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6634339/
https://www.ncbi.nlm.nih.gov/pubmed/31328071
http://dx.doi.org/10.7759/cureus.4680
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author Agrawal, Ankit
Pabolu, Sangeetha
author_facet Agrawal, Ankit
Pabolu, Sangeetha
author_sort Agrawal, Ankit
collection PubMed
description Idiopathic granulomatous mastitis (IGM) is a rare, benign, and chronic inflammatory condition of the breast. Women of child-bearing age with a recent history of pregnancy and lactation are usually affected, and clinical picture mimics inflammatory breast cancer or breast abscess. The etiology is not well defined but proposed to be a localized immune reaction to the breast tissue. Here, we report a case of a 41-year-old female who presented with left breast pain and discharge and a clinical diagnosis of breast abscess was made. No improvement with antibiotics was noted and she underwent mammography and diagnostic ultrasound of the affected breast. A biopsy of the lesion was obtained which revealed chronic granulomatous inflammation confirming the diagnosis of IGM. She was also found to have hyperprolactinemia secondary to a prolactinoma following which the patient was started on steroid and bromocriptine.
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spelling pubmed-66343392019-07-19 A Rare Case of Idiopathic Granulomatous Mastitis in a Nulliparous Woman with Hyperprolactinemia Agrawal, Ankit Pabolu, Sangeetha Cureus Endocrinology/Diabetes/Metabolism Idiopathic granulomatous mastitis (IGM) is a rare, benign, and chronic inflammatory condition of the breast. Women of child-bearing age with a recent history of pregnancy and lactation are usually affected, and clinical picture mimics inflammatory breast cancer or breast abscess. The etiology is not well defined but proposed to be a localized immune reaction to the breast tissue. Here, we report a case of a 41-year-old female who presented with left breast pain and discharge and a clinical diagnosis of breast abscess was made. No improvement with antibiotics was noted and she underwent mammography and diagnostic ultrasound of the affected breast. A biopsy of the lesion was obtained which revealed chronic granulomatous inflammation confirming the diagnosis of IGM. She was also found to have hyperprolactinemia secondary to a prolactinoma following which the patient was started on steroid and bromocriptine. Cureus 2019-05-16 /pmc/articles/PMC6634339/ /pubmed/31328071 http://dx.doi.org/10.7759/cureus.4680 Text en Copyright © 2019, Agrawal et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Agrawal, Ankit
Pabolu, Sangeetha
A Rare Case of Idiopathic Granulomatous Mastitis in a Nulliparous Woman with Hyperprolactinemia
title A Rare Case of Idiopathic Granulomatous Mastitis in a Nulliparous Woman with Hyperprolactinemia
title_full A Rare Case of Idiopathic Granulomatous Mastitis in a Nulliparous Woman with Hyperprolactinemia
title_fullStr A Rare Case of Idiopathic Granulomatous Mastitis in a Nulliparous Woman with Hyperprolactinemia
title_full_unstemmed A Rare Case of Idiopathic Granulomatous Mastitis in a Nulliparous Woman with Hyperprolactinemia
title_short A Rare Case of Idiopathic Granulomatous Mastitis in a Nulliparous Woman with Hyperprolactinemia
title_sort rare case of idiopathic granulomatous mastitis in a nulliparous woman with hyperprolactinemia
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6634339/
https://www.ncbi.nlm.nih.gov/pubmed/31328071
http://dx.doi.org/10.7759/cureus.4680
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