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Discovery of potential urine-accessible metabolite biomarkers associated with muscle disease and corticosteroid response in the mdx mouse model for Duchenne

Urine is increasingly being considered as a source of biomarker development in Duchenne Muscular Dystrophy (DMD), a severe, life-limiting disorder that affects approximately 1 in 4500 boys. In this study, we considered the mdx mice—a murine model of DMD—to discover biomarkers of disease, as well as...

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Detalles Bibliográficos
Autores principales:	Thangarajh, Mathula, Zhang, Aiping, Gill, Kirandeep, Ressom, Habtom W., Li, Zhenzhi, Varghese, Rency S., Hoffman, Eric P., Nagaraju, Kanneboyina, Hathout, Yetrib, Boca, Simina M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6634414/ https://www.ncbi.nlm.nih.gov/pubmed/31310630 http://dx.doi.org/10.1371/journal.pone.0219507

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