Concerns for efficacy of a 30-valent M-protein-based Streptococcus pyogenes vaccine in regions with high rates of rheumatic heart disease

The prevalence of rheumatic heart disease (RHD) in the Aboriginal population of the Australian Northern Territory is high, and Streptococcus pyogenes skin infections likely contribute to this. A promising candidate S. pyogenes “30mer” vaccine is composed of 30 pharyngitis associated type-specific an...

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Detalles Bibliográficos
Autores principales: Giffard, Philip M., Tong, Steven Y. C., Holt, Deborah C., Ralph, Anna P., Currie, Bart J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6634427/
https://www.ncbi.nlm.nih.gov/pubmed/31269021
http://dx.doi.org/10.1371/journal.pntd.0007511

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