Evaluation of Rapid Diagnostic Tests for Assessment of Hepatitis B in Resource-Limited Settings

Chronic Hepatitis B (HBV) is the most important cause of liver disease worldwide. There is a need for low-cost tests to aid in diagnosis and management of HBV infection in resource-limited settings. We evaluated the utility of several rapid diagnostic tests (RDT) in three different continents (Europ...

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Detalles Bibliográficos
Autores principales: Leathers, James S., Pisano, M. Belen, Re, Viviana, van Oord, Gertine, Sultan, Amir, Boonstra, Andre, Debes, Jose D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ubiquity Press 2019
Materias:
Letters to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6634443/
https://www.ncbi.nlm.nih.gov/pubmed/31276335
http://dx.doi.org/10.5334/aogh.2562
Descripción
Sumario:Chronic Hepatitis B (HBV) is the most important cause of liver disease worldwide. There is a need for low-cost tests to aid in diagnosis and management of HBV infection in resource-limited settings. We evaluated the utility of several rapid diagnostic tests (RDT) in three different continents (Europe, South America, Africa). The HBsAg RDT showed optimal sensitivity and specificity. The anti-HBeAb RDT showed acceptable sensitivity and excellent specificity. Our results suggest that these RDTs could be used for screening and management of HBV.

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