Evaluation of Rapid Diagnostic Tests for Assessment of Hepatitis B in Resource-Limited Settings

Chronic Hepatitis B (HBV) is the most important cause of liver disease worldwide. There is a need for low-cost tests to aid in diagnosis and management of HBV infection in resource-limited settings. We evaluated the utility of several rapid diagnostic tests (RDT) in three different continents (Europ...

Descripción completa

Detalles Bibliográficos
Autores principales: Leathers, James S., Pisano, M. Belen, Re, Viviana, van Oord, Gertine, Sultan, Amir, Boonstra, Andre, Debes, Jose D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ubiquity Press 2019
Materias:
Letters to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6634443/
https://www.ncbi.nlm.nih.gov/pubmed/31276335
http://dx.doi.org/10.5334/aogh.2562
_version_ 1783435788971671552
author Leathers, James S.
Pisano, M. Belen
Re, Viviana
van Oord, Gertine
Sultan, Amir
Boonstra, Andre
Debes, Jose D.
author_facet Leathers, James S.
Pisano, M. Belen
Re, Viviana
van Oord, Gertine
Sultan, Amir
Boonstra, Andre
Debes, Jose D.
author_sort Leathers, James S.
collection PubMed
description Chronic Hepatitis B (HBV) is the most important cause of liver disease worldwide. There is a need for low-cost tests to aid in diagnosis and management of HBV infection in resource-limited settings. We evaluated the utility of several rapid diagnostic tests (RDT) in three different continents (Europe, South America, Africa). The HBsAg RDT showed optimal sensitivity and specificity. The anti-HBeAb RDT showed acceptable sensitivity and excellent specificity. Our results suggest that these RDTs could be used for screening and management of HBV.
format Online
Article
Text
id pubmed-6634443
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Ubiquity Press
record_format MEDLINE/PubMed
spelling pubmed-66344432019-09-16 Evaluation of Rapid Diagnostic Tests for Assessment of Hepatitis B in Resource-Limited Settings Leathers, James S. Pisano, M. Belen Re, Viviana van Oord, Gertine Sultan, Amir Boonstra, Andre Debes, Jose D. Ann Glob Health Letters to the Editor Chronic Hepatitis B (HBV) is the most important cause of liver disease worldwide. There is a need for low-cost tests to aid in diagnosis and management of HBV infection in resource-limited settings. We evaluated the utility of several rapid diagnostic tests (RDT) in three different continents (Europe, South America, Africa). The HBsAg RDT showed optimal sensitivity and specificity. The anti-HBeAb RDT showed acceptable sensitivity and excellent specificity. Our results suggest that these RDTs could be used for screening and management of HBV. Ubiquity Press 2019-07-04 /pmc/articles/PMC6634443/ /pubmed/31276335 http://dx.doi.org/10.5334/aogh.2562 Text en Copyright: © 2019 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC-BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See http://creativecommons.org/licenses/by/4.0/.
spellingShingle Letters to the Editor
Leathers, James S.
Pisano, M. Belen
Re, Viviana
van Oord, Gertine
Sultan, Amir
Boonstra, Andre
Debes, Jose D.
Evaluation of Rapid Diagnostic Tests for Assessment of Hepatitis B in Resource-Limited Settings
title Evaluation of Rapid Diagnostic Tests for Assessment of Hepatitis B in Resource-Limited Settings
title_full Evaluation of Rapid Diagnostic Tests for Assessment of Hepatitis B in Resource-Limited Settings
title_fullStr Evaluation of Rapid Diagnostic Tests for Assessment of Hepatitis B in Resource-Limited Settings
title_full_unstemmed Evaluation of Rapid Diagnostic Tests for Assessment of Hepatitis B in Resource-Limited Settings
title_short Evaluation of Rapid Diagnostic Tests for Assessment of Hepatitis B in Resource-Limited Settings
title_sort evaluation of rapid diagnostic tests for assessment of hepatitis b in resource-limited settings
topic Letters to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6634443/
https://www.ncbi.nlm.nih.gov/pubmed/31276335
http://dx.doi.org/10.5334/aogh.2562
work_keys_str_mv AT leathersjamess evaluationofrapiddiagnostictestsforassessmentofhepatitisbinresourcelimitedsettings
AT pisanombelen evaluationofrapiddiagnostictestsforassessmentofhepatitisbinresourcelimitedsettings
AT reviviana evaluationofrapiddiagnostictestsforassessmentofhepatitisbinresourcelimitedsettings
AT vanoordgertine evaluationofrapiddiagnostictestsforassessmentofhepatitisbinresourcelimitedsettings
AT sultanamir evaluationofrapiddiagnostictestsforassessmentofhepatitisbinresourcelimitedsettings
AT boonstraandre evaluationofrapiddiagnostictestsforassessmentofhepatitisbinresourcelimitedsettings
AT debesjosed evaluationofrapiddiagnostictestsforassessmentofhepatitisbinresourcelimitedsettings

Ejemplares similares