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The transcription factor Hey and nuclear lamins specify and maintain cell identity

The inability of differentiated cells to maintain their identity is a hallmark of age-related diseases. We found that the transcription factor Hey supervises the identity of differentiated enterocytes (ECs) in the adult Drosophila midgut. Lineage tracing established that Hey-deficient ECs are unable...

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Detalles Bibliográficos
Autores principales: Flint Brodsly, Naama, Bitman-Lotan, Eliya, Boico, Olga, Shafat, Adi, Monastirioti, Maria, Gessler, Manfred, Delidakis, Christos, Rincon-Arano, Hector, Orian, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6634966/
https://www.ncbi.nlm.nih.gov/pubmed/31310235
http://dx.doi.org/10.7554/eLife.44745