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A zwitterionic near-infrared fluorophore for real-time ureter identification during laparoscopic abdominopelvic surgery

Iatrogenic injury of the ureters is a feared complication of abdominal surgery. Zwitterionic near-infrared fluorophores are molecules with geometrically-balanced, electrically-neutral surface charge, which leads to renal-exclusive clearance and ultralow non-specific background binding. Such molecule...

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Detalles Bibliográficos
Autores principales: de Valk, Kim S., Handgraaf, Henricus J., Deken, Marion M., Sibinga Mulder, Babs G., Valentijn, Adrianus R., Terwisscha van Scheltinga, Anton G., Kuil, Joeri, van Esdonk, Michiel J., Vuijk, Jaap, Bevers, Rob F., Peeters, Koen C., Holman, Fabian A., Frangioni, John V., Burggraaf, Jacobus, Vahrmeijer, Alexander L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635391/
https://www.ncbi.nlm.nih.gov/pubmed/31311922
http://dx.doi.org/10.1038/s41467-019-11014-1