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A zwitterionic near-infrared fluorophore for real-time ureter identification during laparoscopic abdominopelvic surgery
Iatrogenic injury of the ureters is a feared complication of abdominal surgery. Zwitterionic near-infrared fluorophores are molecules with geometrically-balanced, electrically-neutral surface charge, which leads to renal-exclusive clearance and ultralow non-specific background binding. Such molecule...
Autores principales: | de Valk, Kim S., Handgraaf, Henricus J., Deken, Marion M., Sibinga Mulder, Babs G., Valentijn, Adrianus R., Terwisscha van Scheltinga, Anton G., Kuil, Joeri, van Esdonk, Michiel J., Vuijk, Jaap, Bevers, Rob F., Peeters, Koen C., Holman, Fabian A., Frangioni, John V., Burggraaf, Jacobus, Vahrmeijer, Alexander L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635391/ https://www.ncbi.nlm.nih.gov/pubmed/31311922 http://dx.doi.org/10.1038/s41467-019-11014-1 |
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