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Systematic allelic analysis defines the interplay of key pathways in X chromosome inactivation

Xist RNA, the master regulator of X chromosome inactivation, acts in cis to induce chromosome-wide silencing. Whilst recent studies have defined candidate silencing factors, their relative contribution to repressing different genes, and their relationship with one another is poorly understood. Here...

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Detalles Bibliográficos
Autores principales: Nesterova, Tatyana B., Wei, Guifeng, Coker, Heather, Pintacuda, Greta, Bowness, Joseph S., Zhang, Tianyi, Almeida, Mafalda, Bloechl, Bianca, Moindrot, Benoit, Carter, Emma J., Alvarez Rodrigo, Ines, Pan, Qi, Bi, Ying, Song, Chun-Xiao, Brockdorff, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635394/
https://www.ncbi.nlm.nih.gov/pubmed/31311937
http://dx.doi.org/10.1038/s41467-019-11171-3