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Improved In vivo Effect of Chrysin as an Absorption Enhancer Via the Preparation of Ternary Solid Dispersion with Brij(®)L4 and Aminoclay

BACKGROUND: Chrysin is a strong inhibitor of breast cancer resistance protein (BCRP) but it is practically insoluble in water. Effective solubilization of chrysin is critical for its pharmaceutical application as an absorption enhancer via inhibition of BCRP-mediated drug efflux. OBJECTIVE: This stu...

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Detalles Bibliográficos
Autores principales:	Lee, Sang Hoon, Lee, Yeo-song, Song, Jae Geun, Han, Hyo-Kyung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635418/ https://www.ncbi.nlm.nih.gov/pubmed/30246640 http://dx.doi.org/10.2174/1567201815666180924151458

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