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Oxidative and Inflammatory Events in Prion Diseases: Can they Be Therapeutic Targets?

Prion diseases are a group of incurable infectious terminal neurodegenerative diseases caused by the aggregated misfolded PrPsc in selected mammals including humans. The complex physical interaction between normal prion protein PrPc and infectious PrPsc causes conformational change from the α- helix...

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Detalles Bibliográficos
Autores principales: Prasad, Kedar N., Bondy, Stephen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635421/
https://www.ncbi.nlm.nih.gov/pubmed/30636622
http://dx.doi.org/10.2174/1874609812666190111100205

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