Patient-derived pancreas-on-a-chip to model cystic fibrosis-related disorders

Cystic fibrosis (CF) is a genetic disorder caused by defective CF Transmembrane Conductance Regulator (CFTR) function. Insulin producing pancreatic islets are located in close proximity to the pancreatic duct and there is a possibility of impaired cell-cell signaling between pancreatic ductal epithe...

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Detalles Bibliográficos
Autores principales: Shik Mun, Kyu, Arora, Kavisha, Huang, Yunjie, Yang, Fanmuyi, Yarlagadda, Sunitha, Ramananda, Yashaswini, Abu-El-Haija, Maisam, Palermo, Joseph J., Appakalai, Balamurugan N., Nathan, Jaimie D., Naren, Anjaparavanda P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635497/
https://www.ncbi.nlm.nih.gov/pubmed/31311920
http://dx.doi.org/10.1038/s41467-019-11178-w

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