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Atrogin-1/MAFbx mRNA expression is regulated by histone deacetylase 1 in rat soleus muscle under hindlimb unloading

It is known that MuRF-1 and atrogin-1/MAFbx mRNA expression is increased in rat soleus muscle under unloading conditions. We aimed to determine the role of histone deacetylase 1 (HDAC1) in the activation of MuRF-1 and MAFbx expression in rat soleus muscle at the early stage of hindlimb suspension (H...

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Detalles Bibliográficos
Autores principales: Mochalova, Ekaterina P., Belova, Svetlana P., Mirzoev, Timur M., Shenkman, Boris S., Nemirovskaya, Tatiana L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635498/
https://www.ncbi.nlm.nih.gov/pubmed/31311969
http://dx.doi.org/10.1038/s41598-019-46753-0