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Causes and Effects of Loss of Classical Nonhomologous End Joining Pathway in Parasitic Eukaryotes

We report frequent losses of components of the classical nonhomologous end joining pathway (C-NHEJ), one of the main eukaryotic tools for end joining repair of DNA double-strand breaks, in several lineages of parasitic protists. Moreover, we have identified a single lineage among trypanosomatid flag...

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Detalles Bibliográficos
Autores principales:	Nenarokova, Anna, Záhonová, Kristína, Krasilnikova, Marija, Gahura, Ondřej, McCulloch, Richard, Zíková, Alena, Yurchenko, Vyacheslav, Lukeš, Julius
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Observation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635534/ https://www.ncbi.nlm.nih.gov/pubmed/31311886 http://dx.doi.org/10.1128/mBio.01541-19

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