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A live cell NanoBRET binding assay allows the study of ligand-binding kinetics to the adenosine A(3) receptor
There is a growing interest in understanding the binding kinetics of compounds that bind to G protein-coupled receptors prior to progressing a lead compound into clinical trials. The widely expressed adenosine A(3) receptor (A(3)AR) has been implicated in a range of diseases including immune conditi...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Netherlands
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635573/ https://www.ncbi.nlm.nih.gov/pubmed/30919204 http://dx.doi.org/10.1007/s11302-019-09650-9 |