Survey of Drug Oxidation Activities in Hepatic and Intestinal Microsomes of Individual Common Marmosets, a New Nonhuman Primate Animal Model

BACKGROUND: Common marmosets (Callithrix jacchus) are potentially useful non-human primate models for preclinical studies. Information for major drug-metabolizing cyto-chrome P450 (P450) enzymes is now available that supports the use of this primate species as an animal model for drug development. H...

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Detalles Bibliográficos
Autores principales: Uehara, Shotaro, Oshio, Toru, Nakanishi, Kazuyuki, Tomioka, Etsuko, Suzuki, Miyu, Inoue, Takashi, Uno, Yasuhiro, Sasaki, Erika, Yamazaki, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635653/
https://www.ncbi.nlm.nih.gov/pubmed/30280664
http://dx.doi.org/10.2174/1389200219666181003143312

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