Cargando…

Nobiletin Inhibits Cell Viability via the SRC/AKT/STAT3/YY1AP1 Pathway in Human Renal Carcinoma Cells

Nobiletin is a polymethoxy flavonoid isolated from Citrus depressa and Citrus reticulata. It has been reported that nobiletin can suppress tumors. We primarily explored the antitumor effects of nobiletin and the associated potential mechanisms in ACHN and Caki-2 renal carcinoma cells. A CCK-8 assay...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wei, Di, Zhang, Geng, Zhu, Zheng, Zheng, Yu, Yan, Fei, Pan, Chongxian, Wang, Zhiyong, Li, Xian, Wang, Fuli, Meng, Ping, Zheng, Wanxiang, Yan, Zhao, Zhai, Dongsheng, Lu, Zifan, Yuan, Jianlin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635658/ https://www.ncbi.nlm.nih.gov/pubmed/31354472 http://dx.doi.org/10.3389/fphar.2019.00690

Ejemplares similares

Nobiletin Inhibits Angiogenesis by Regulating Src/FAK/STAT3-Mediated Signaling through PXN in ER(+) Breast Cancer Cells
por: Sp, Nipin, et al.
Publicado: (2017)

CapsNetYY1: identifying YY1-mediated chromatin loops based on a capsule network architecture
por: Zhang, Zhimin, et al.
Publicado: (2023)

The RNA-binding protein QKI suppresses tumorigenesis of clear cell renal cell carcinoma by regulating the expression of HIF-1α
por: Shi, Fei, et al.
Publicado: (2020)

Flavonoid Nobiletin Exhibits Differential Effects on Cell Viability in Keratinocytes Exposed to UVA versus UVB Radiation
por: Cvammen, William, et al.
Publicado: (2022)

Nobiletin suppresses cell viability through AKT Pathways in PC-3 and DU-145 prostate cancer cells
por: Chen, Jianchu, et al.
Publicado: (2014)

Integrative Genomics Identifies YY1AP1 as an Oncogenic Driver in EpCAM(+) AFP(+) Hepatocellular Carcinoma
por: Zhao, Xuelian, et al.
Publicado: (2015)

Identification of pathogenic YY1AP1 splice variants in siblings with Grange syndrome by whole exome sequencing
por: Rath, Matthias, et al.
Publicado: (2018)

Datasets of YY1 expression in rheumatoid arthritis patients
por: Lin, Jinpiao, et al.
Publicado: (2016)

YY1 suppresses FEN1 over-expression and drug resistance in breast cancer
por: Wang, Jianwei, et al.
Publicado: (2015)

FBP1 /miR-24-1/enhancer axis activation blocks renal cell carcinoma progression via Warburg effect
por: Ju, Dongen, et al.
Publicado: (2022)

Deletion of discoidin domain receptor 2 attenuates renal interstitial fibrosis in a murine unilateral ureteral obstruction model
por: Li, Xi’an, et al.
Publicado: (2019)

Nobiletin Delays Aging and Enhances Stress Resistance of Caenorhabditis elegans
por: Yang, Xueyan, et al.
Publicado: (2020)

Retroposition and evolution of the DNA-binding motifs of YY1, YY2 and REX1
por: Kim, Jeong Do, et al.
Publicado: (2007)

Genome-wide analysis of YY2 versus YY1 target genes
por: Chen, Li, et al.
Publicado: (2010)

Nobiletin, a citrus polymethoxyflavone, enhances the effects of bicalutamide on prostate cancer cells via down regulation of NF-κB, STAT3, and ERK activation
por: Ma, Yuran, et al.
Publicado: (2020)

Nobiletin enhances the efficacy of chemotherapeutic agents in ABCB1 overexpression cancer cells
por: Ma, Wenzhe, et al.
Publicado: (2015)

SRC-1 and Twist1 are prognostic indicators of liver cancer and are associated with cell viability, invasion, migration and epithelial-mesenchymal transformation of hepatocellular carcinoma cells
por: Zhao, Peng-Wei, et al.
Publicado: (2020)

Homeostasis Imbalance of YY2 and YY1 Promotes Tumor Growth by Manipulating Ferroptosis
por: Li, Yanjun, et al.
Publicado: (2022)

Effect of Nobiletin on Experimental Model of Epilepsy
por: Yang, Baowang, et al.
Publicado: (2018)

Dissecting the roles and clinical potential of YY1 in the tumor microenvironment
por: Li, MengNa, et al.
Publicado: (2023)

Novel survival nomograms for patients with lung metastatic clear cell renal cell carcinoma: A population-based study
por: Zhang, Lei, et al.
Publicado: (2020)

Cistrome analysis of YY1 uncovers a regulatory axis of YY1:BRD2/4-PFKP during tumorigenesis of advanced prostate cancer
por: Xu, Chenxi, et al.
Publicado: (2021)

Endothelial specific YY1 deletion restricts tumor angiogenesis and tumor growth
por: Liu, Huan, et al.
Publicado: (2020)

The combined immunodetection of AP-2α and YY1 transcription factors is associated with ERBB2 gene overexpression in primary breast tumors
por: Allouche, Abdelkader, et al.
Publicado: (2008)

Nobiletin suppresses cholangiocarcinoma proliferation via inhibiting GSK3β
por: You, Liping, et al.
Publicado: (2022)

Dysregulated YY1/PRMT5 axis promotes the progression and metastasis of laryngeal cancer by targeting Hippo pathway
por: Wang, Nan, et al.
Publicado: (2020)

Peptide encoded by lncRNA BVES-AS1 promotes cell viability, migration, and invasion in colorectal cancer cells via the SRC/mTOR signaling pathway
por: Zheng, Weiwei, et al.
Publicado: (2023)

Indirubin suppresses ovarian cancer cell viabilities through the STAT3 signaling pathway
por: Chen, Lihong, et al.
Publicado: (2018)

Androgen receptor-mediated upregulation of quaking affects androgen receptor-related prostate cancer development and anti-androgen receptor therapy
por: Zhang, Keke, et al.
Publicado: (2018)

Quercetin Induces Apoptosis in HepG2 Cells via Directly Interacting with YY1 to Disrupt YY1-p53 Interaction
por: Guan, Hui, et al.
Publicado: (2023)

Nobiletin Improves D-Galactose-Induced Aging Mice Skeletal Muscle Atrophy by Regulating Protein Homeostasis
por: Wang, Hui-Hui, et al.
Publicado: (2023)

Crosstalk between YY1 and lncRNAs in cancer: A review
por: Wang, Xiao-li, et al.
Publicado: (2022)

Nobiletin Inhibits Inflammatory Reaction in Interleukin-1β-Stimulated Human Periodontal Ligament Cells
por: Hosokawa, Yoshitaka, et al.
Publicado: (2021)

Pharmacological actions of nobiletin in the modulation of platelet function
por: Vaiyapuri, Sakthivel, et al.
Publicado: (2015)

Transdermal delivery of nobiletin using ionic liquids
por: Hattori, Tadashi, et al.
Publicado: (2019)

YY1 Is Required for Germinal Center B Cell Development
por: Banerjee, Anupam, et al.
Publicado: (2016)

Whole genome sequencing reveals a frameshift mutation and a large deletion in YY1AP1 in a girl with a panvascular artery disease
por: Raggio, Víctor, et al.
Publicado: (2021)

Ring 1 and YY1 Binding Protein is Expressed in Murine Spermatocytes but Dispensable for Spermatogenesis
por: He, Zhen, et al.
Publicado: (2020)

JAC1 targets YY1 mediated JWA/p38 MAPK signaling to inhibit proliferation and induce apoptosis in TNBC
por: Zhai, Zurong, et al.
Publicado: (2022)

Nobiletin induces growth inhibition and apoptosis in human nasopharyngeal carcinoma C666‐1 cells through regulating PARP‐2/SIRT1/AMPK signaling pathway
por: Zheng, Guo Dong, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ni8s2eb28tcgktbg108ua8jrb3