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Can Wideband Tympanometry Be Used as a Screening Test for Superior Semicircular Canal Dehiscence?

OBJECTIVES: We explored whether wideband tympanometry (WBT) could be used as a screening test for superior semicircular canal dehiscence (SSCD), and obtained new WBT data (given that the test is not yet in common clinical use) on patients with SSCD. METHODS: We compared the WBT data of patients clin...

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Autores principales: Demir, Emine, Afacan, Nazife Nur, Celiker, Metin, Celiker, Fatma Beyazal, İnecikli, Mehmet Fatih, Terzi, Suat, Dursun, Engin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Otorhinolaryngology-Head and Neck Surgery 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635713/
https://www.ncbi.nlm.nih.gov/pubmed/30458602
http://dx.doi.org/10.21053/ceo.2018.01137
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author Demir, Emine
Afacan, Nazife Nur
Celiker, Metin
Celiker, Fatma Beyazal
İnecikli, Mehmet Fatih
Terzi, Suat
Dursun, Engin
author_facet Demir, Emine
Afacan, Nazife Nur
Celiker, Metin
Celiker, Fatma Beyazal
İnecikli, Mehmet Fatih
Terzi, Suat
Dursun, Engin
author_sort Demir, Emine
collection PubMed
description OBJECTIVES: We explored whether wideband tympanometry (WBT) could be used as a screening test for superior semicircular canal dehiscence (SSCD), and obtained new WBT data (given that the test is not yet in common clinical use) on patients with SSCD. METHODS: We compared the WBT data of patients clinically and radiologically diagnosed with SSCD in our hospital between 2013 and 2018 to those of healthy volunteers. We compared the resonance frequency (RF), maximum absorbance frequency (MAF), and maximum absorbance ratio (MAR). The t-test was used for statistical analysis with the significance level set to P<0.05. In addition, we used receiver operating characteristic analysis to derive cutoff values for SSCD diagnosis in terms of sensitivity and specificity. RESULTS: Seventeen patients (four with bilateral and 13 with unilateral disease; 17 ears) diagnosed with SSCD and 27 healthy volunteers (47 ears) were included. The mean RFs of the SSCD patients and healthy subjects were 548.7 Hz (range, 243 to 853 Hz) and 935.1 Hz (range, 239 to 1,875 Hz), respectively (P<0.001). The mean MARs of the SSCD patients and healthy subjects were 89.4% (range, 62% to 100%) and 82.4% (range, 63% to 99%), respectively (P=0.005). The mean MAFs of the SSCD patients and healthy subjects were 1,706.3 Hz (range, 613 to 3,816 Hz) and 2,668 Hz (range, 876 to 4,387 Hz), respectively (P<0.001). In terms of SSCD diagnosis, a MAR above 86% afforded 81% sensitivity and 77% specificity; an RF below 728 Hz, 86% sensitivity and 81% specificity; and an MAF below 1,835 Hz, 79% sensitivity and 67% specificity. CONCLUSION: WBT may be a useful clinical screening test for SSCD. The RF and MAF were lower, and the MAR higher, in SSCD patients than in normal controls.
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spelling pubmed-66357132019-08-15 Can Wideband Tympanometry Be Used as a Screening Test for Superior Semicircular Canal Dehiscence? Demir, Emine Afacan, Nazife Nur Celiker, Metin Celiker, Fatma Beyazal İnecikli, Mehmet Fatih Terzi, Suat Dursun, Engin Clin Exp Otorhinolaryngol Original Article OBJECTIVES: We explored whether wideband tympanometry (WBT) could be used as a screening test for superior semicircular canal dehiscence (SSCD), and obtained new WBT data (given that the test is not yet in common clinical use) on patients with SSCD. METHODS: We compared the WBT data of patients clinically and radiologically diagnosed with SSCD in our hospital between 2013 and 2018 to those of healthy volunteers. We compared the resonance frequency (RF), maximum absorbance frequency (MAF), and maximum absorbance ratio (MAR). The t-test was used for statistical analysis with the significance level set to P<0.05. In addition, we used receiver operating characteristic analysis to derive cutoff values for SSCD diagnosis in terms of sensitivity and specificity. RESULTS: Seventeen patients (four with bilateral and 13 with unilateral disease; 17 ears) diagnosed with SSCD and 27 healthy volunteers (47 ears) were included. The mean RFs of the SSCD patients and healthy subjects were 548.7 Hz (range, 243 to 853 Hz) and 935.1 Hz (range, 239 to 1,875 Hz), respectively (P<0.001). The mean MARs of the SSCD patients and healthy subjects were 89.4% (range, 62% to 100%) and 82.4% (range, 63% to 99%), respectively (P=0.005). The mean MAFs of the SSCD patients and healthy subjects were 1,706.3 Hz (range, 613 to 3,816 Hz) and 2,668 Hz (range, 876 to 4,387 Hz), respectively (P<0.001). In terms of SSCD diagnosis, a MAR above 86% afforded 81% sensitivity and 77% specificity; an RF below 728 Hz, 86% sensitivity and 81% specificity; and an MAF below 1,835 Hz, 79% sensitivity and 67% specificity. CONCLUSION: WBT may be a useful clinical screening test for SSCD. The RF and MAF were lower, and the MAR higher, in SSCD patients than in normal controls. Korean Society of Otorhinolaryngology-Head and Neck Surgery 2019-08 2018-11-22 /pmc/articles/PMC6635713/ /pubmed/30458602 http://dx.doi.org/10.21053/ceo.2018.01137 Text en Copyright © 2019 by Korean Society of Otorhinolaryngology-Head and Neck Surgery This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Demir, Emine
Afacan, Nazife Nur
Celiker, Metin
Celiker, Fatma Beyazal
İnecikli, Mehmet Fatih
Terzi, Suat
Dursun, Engin
Can Wideband Tympanometry Be Used as a Screening Test for Superior Semicircular Canal Dehiscence?
title Can Wideband Tympanometry Be Used as a Screening Test for Superior Semicircular Canal Dehiscence?
title_full Can Wideband Tympanometry Be Used as a Screening Test for Superior Semicircular Canal Dehiscence?
title_fullStr Can Wideband Tympanometry Be Used as a Screening Test for Superior Semicircular Canal Dehiscence?
title_full_unstemmed Can Wideband Tympanometry Be Used as a Screening Test for Superior Semicircular Canal Dehiscence?
title_short Can Wideband Tympanometry Be Used as a Screening Test for Superior Semicircular Canal Dehiscence?
title_sort can wideband tympanometry be used as a screening test for superior semicircular canal dehiscence?
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635713/
https://www.ncbi.nlm.nih.gov/pubmed/30458602
http://dx.doi.org/10.21053/ceo.2018.01137
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