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Enforced microglial depletion and repopulation as a promising strategy for the treatment of neurological disorders

Microglia are prominent immune cells in the central nervous system (CNS) and are critical players in both neurological development and homeostasis, and in neurological diseases when dysfunctional. Our previous understanding of the phenotypes and functions of microglia has been greatly extended by a...

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Detalles Bibliográficos
Autores principales: Han, Jinming, Zhu, Keying, Zhang, Xing‐Mei, Harris, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635749/
https://www.ncbi.nlm.nih.gov/pubmed/30378163
http://dx.doi.org/10.1002/glia.23529