IL4Rα Signaling Abrogates Hypoxic Neutrophil Survival and Limits Acute Lung Injury Responses In Vivo

Rationale: Acute respiratory distress syndrome is defined by the presence of systemic hypoxia and consequent on disordered neutrophilic inflammation. Local mechanisms limiting the duration and magnitude of this neutrophilic response remain poorly understood. Objectives: To test the hypothesis that d...

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Detalles Bibliográficos
Autores principales: Harris, Alison J., Mirchandani, Ananda S., Lynch, Ruairi W., Murphy, Fiona, Delaney, Liam, Small, Donna, Coelho, Patricia, Watts, Emily R., Sadiku, Pranvera, Griffith, David, Dickinson, Rebecca S., Clark, Eilidh, Willson, Joseph A., Morrison, Tyler, Mazzone, Massimilliano, Carmeliet, Peter, Ghesquiere, Bart, O’Kane, Cecilia, McAuley, Danny, Jenkins, Steve J., Whyte, Moira K. B., Walmsley, Sarah R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Thoracic Society 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635795/
https://www.ncbi.nlm.nih.gov/pubmed/30849228
http://dx.doi.org/10.1164/rccm.201808-1599OC

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635795/
https://www.ncbi.nlm.nih.gov/pubmed/30849228
http://dx.doi.org/10.1164/rccm.201808-1599OC

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