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A Biochemical Nickel(I) State Supports Nucleophilic Alkyl Addition: A Roadmap for Methyl Reactivity in Acetyl Coenzyme A Synthase

[Image: see text] Nickel-containing enzymes such as methyl coenzyme M reductase (MCR) and carbon monoxide dehydrogenase/acetyl coenzyme A synthase (CODH/ACS) play a critical role in global energy conversion reactions, with significant contributions to carbon-centered processes. These enzymes are imp...

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Detalles Bibliográficos
Autores principales:	Manesis, Anastasia C., Musselman, Bradley W., Keegan, Brenna C., Shearer, Jason, Lehnert, Nicolai, Shafaat, Hannah S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2019
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635881/ https://www.ncbi.nlm.nih.gov/pubmed/30788970 http://dx.doi.org/10.1021/acs.inorgchem.8b03546

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