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Disruption of nuclear speckles reduces chromatin interactions in active compartments

BACKGROUND: Nuclei of eukaryotes contain various higher-order chromatin architectures and nuclear bodies (NBs), which are critical for proper nuclear functions. Recent studies showed that active chromatin regions are associated with nuclear speckles (NSs), a type of NBs involved in RNA processing. H...

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Detalles Bibliográficos
Autores principales:	Hu, Shibin, Lv, Pin, Yan, Zixiang, Wen, Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636040/ https://www.ncbi.nlm.nih.gov/pubmed/31315647 http://dx.doi.org/10.1186/s13072-019-0289-2

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