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Comparative study of cytotoxic effects induced by environmental genotoxins using XPC- and CSB-deficient human lymphoblastoid TK6 cells
BACKGROUND: The human genome is constantly exposed to numerous environmental genotoxicants. To prevent the detrimental consequences induced by the expansion of damaged cells, cellular protective systems such as nucleotide excision repair (NER) exist and serve as a primary pathway for repairing the v...
Autores principales: | Sassa, Akira, Fukuda, Takayuki, Ukai, Akiko, Nakamura, Maki, Takabe, Michihito, Takamura-Enya, Takeji, Honma, Masamitsu, Yasui, Manabu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636061/ https://www.ncbi.nlm.nih.gov/pubmed/31346351 http://dx.doi.org/10.1186/s41021-019-0130-y |
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