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Comparative study of cytotoxic effects induced by environmental genotoxins using XPC- and CSB-deficient human lymphoblastoid TK6 cells

BACKGROUND: The human genome is constantly exposed to numerous environmental genotoxicants. To prevent the detrimental consequences induced by the expansion of damaged cells, cellular protective systems such as nucleotide excision repair (NER) exist and serve as a primary pathway for repairing the v...

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Detalles Bibliográficos
Autores principales: Sassa, Akira, Fukuda, Takayuki, Ukai, Akiko, Nakamura, Maki, Takabe, Michihito, Takamura-Enya, Takeji, Honma, Masamitsu, Yasui, Manabu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636061/
https://www.ncbi.nlm.nih.gov/pubmed/31346351
http://dx.doi.org/10.1186/s41021-019-0130-y

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