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A preliminary analysis of interleukin-1 ligands as potential predictive biomarkers of response to cetuximab

BACKGROUND: The epidermal growth factor receptor (EGFR) monoclonal IgG(1) antibody cetuximab is approved for first-line treatment of recurrent and metastatic (R/M) HNSCC as a part of the standard of care EXTREME regimen (platinum/5-fluorouracil/cetuximab). This regimen has relatively high response a...

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Detalles Bibliográficos
Autores principales:	Espinosa-Cotton, Madelyn, Fertig, Elana J., Stabile, Laura P., Gaither-Davis, Autumn, Bauman, Julie E., Schmitz, Sandra, Gibson-Corley, Katherine N., Cheng, Yinwen, Jensen, Isaac J., Badovinac, Vladimir P., Laux, Douglas, Simons, Andrean L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636109/ https://www.ncbi.nlm.nih.gov/pubmed/31346466 http://dx.doi.org/10.1186/s40364-019-0164-0

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