Cargando…

The anticaries effects of pit and fissure sealant in the first permanent molars of school-age children from Guangzhou: a population-based cohort study

BACKGROUND: Analyses of the effects of pit and fissure sealant have been based on small samples and lack large-scale field evaluation data in China. The aim of this study was to understand the effect of pit and fissure sealant in preventing caries in the first permanent molars (FPMs) of children in...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Weijia, Xiong, Lihua, Li, Jianbo, Guo, Chongshan, Fan, Weihua, Huang, Shaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636114/
https://www.ncbi.nlm.nih.gov/pubmed/31311541
http://dx.doi.org/10.1186/s12903-019-0846-x
_version_ 1783436006839549952
author Liu, Weijia
Xiong, Lihua
Li, Jianbo
Guo, Chongshan
Fan, Weihua
Huang, Shaohong
author_facet Liu, Weijia
Xiong, Lihua
Li, Jianbo
Guo, Chongshan
Fan, Weihua
Huang, Shaohong
author_sort Liu, Weijia
collection PubMed
description BACKGROUND: Analyses of the effects of pit and fissure sealant have been based on small samples and lack large-scale field evaluation data in China. The aim of this study was to understand the effect of pit and fissure sealant in preventing caries in the first permanent molars (FPMs) of children in Guangzhou. METHODS: We conducted a population-based cohort study using the database of the pit and fissure sealant program of Guangzhou. The carious status and sealant retention of the FPMs were assessed in 4,822 school children who received pit and fissure sealant 3 years prior to the study. The control group included 4,396 children who had indications for receiving pit and fissure sealant but were not treated and were matched according to sex, age and school. RESULTS: In the sealant group, the rate of sealant retention in the FPMs was 72.2%. Children in the sealant group had a 37% decreased risk of dental caries compared with the control group (adjusted HR = 0.63 [95% confidence interval (CI), 0.57–0.69], P < 0.001). Compared to no sealant use, the use of pit and fissure sealants reduced the risk of developing dental caries by 44% after 3 years in the FPMs of children from rural areas, reflecting a greater reduction than that among urban children (35%) during the same period (urban: adjusted hazard ratio (HR) = 0.65 [95% CI, 0.58–0.72]; rural: adjusted HR = 0.56 [95% CI, 0.45–0.70], P < 0.001). The mean number of decayed, missing, or filled permanent teeth (DMFT) in the control group was higher than that in the sealant group, and the difference was statistically significant regardless of sex. CONCLUSIONS: Pit and fissure sealant has a significant preventive effect against dental caries in the FPMs, especially for children in rural areas; thus, this sealant represents an effective technique for preventing and controlling dental caries.
format Online
Article
Text
id pubmed-6636114
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-66361142019-07-25 The anticaries effects of pit and fissure sealant in the first permanent molars of school-age children from Guangzhou: a population-based cohort study Liu, Weijia Xiong, Lihua Li, Jianbo Guo, Chongshan Fan, Weihua Huang, Shaohong BMC Oral Health Research Article BACKGROUND: Analyses of the effects of pit and fissure sealant have been based on small samples and lack large-scale field evaluation data in China. The aim of this study was to understand the effect of pit and fissure sealant in preventing caries in the first permanent molars (FPMs) of children in Guangzhou. METHODS: We conducted a population-based cohort study using the database of the pit and fissure sealant program of Guangzhou. The carious status and sealant retention of the FPMs were assessed in 4,822 school children who received pit and fissure sealant 3 years prior to the study. The control group included 4,396 children who had indications for receiving pit and fissure sealant but were not treated and were matched according to sex, age and school. RESULTS: In the sealant group, the rate of sealant retention in the FPMs was 72.2%. Children in the sealant group had a 37% decreased risk of dental caries compared with the control group (adjusted HR = 0.63 [95% confidence interval (CI), 0.57–0.69], P < 0.001). Compared to no sealant use, the use of pit and fissure sealants reduced the risk of developing dental caries by 44% after 3 years in the FPMs of children from rural areas, reflecting a greater reduction than that among urban children (35%) during the same period (urban: adjusted hazard ratio (HR) = 0.65 [95% CI, 0.58–0.72]; rural: adjusted HR = 0.56 [95% CI, 0.45–0.70], P < 0.001). The mean number of decayed, missing, or filled permanent teeth (DMFT) in the control group was higher than that in the sealant group, and the difference was statistically significant regardless of sex. CONCLUSIONS: Pit and fissure sealant has a significant preventive effect against dental caries in the FPMs, especially for children in rural areas; thus, this sealant represents an effective technique for preventing and controlling dental caries. BioMed Central 2019-07-16 /pmc/articles/PMC6636114/ /pubmed/31311541 http://dx.doi.org/10.1186/s12903-019-0846-x Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Liu, Weijia
Xiong, Lihua
Li, Jianbo
Guo, Chongshan
Fan, Weihua
Huang, Shaohong
The anticaries effects of pit and fissure sealant in the first permanent molars of school-age children from Guangzhou: a population-based cohort study
title The anticaries effects of pit and fissure sealant in the first permanent molars of school-age children from Guangzhou: a population-based cohort study
title_full The anticaries effects of pit and fissure sealant in the first permanent molars of school-age children from Guangzhou: a population-based cohort study
title_fullStr The anticaries effects of pit and fissure sealant in the first permanent molars of school-age children from Guangzhou: a population-based cohort study
title_full_unstemmed The anticaries effects of pit and fissure sealant in the first permanent molars of school-age children from Guangzhou: a population-based cohort study
title_short The anticaries effects of pit and fissure sealant in the first permanent molars of school-age children from Guangzhou: a population-based cohort study
title_sort anticaries effects of pit and fissure sealant in the first permanent molars of school-age children from guangzhou: a population-based cohort study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636114/
https://www.ncbi.nlm.nih.gov/pubmed/31311541
http://dx.doi.org/10.1186/s12903-019-0846-x
work_keys_str_mv AT liuweijia theanticarieseffectsofpitandfissuresealantinthefirstpermanentmolarsofschoolagechildrenfromguangzhouapopulationbasedcohortstudy
AT xionglihua theanticarieseffectsofpitandfissuresealantinthefirstpermanentmolarsofschoolagechildrenfromguangzhouapopulationbasedcohortstudy
AT lijianbo theanticarieseffectsofpitandfissuresealantinthefirstpermanentmolarsofschoolagechildrenfromguangzhouapopulationbasedcohortstudy
AT guochongshan theanticarieseffectsofpitandfissuresealantinthefirstpermanentmolarsofschoolagechildrenfromguangzhouapopulationbasedcohortstudy
AT fanweihua theanticarieseffectsofpitandfissuresealantinthefirstpermanentmolarsofschoolagechildrenfromguangzhouapopulationbasedcohortstudy
AT huangshaohong theanticarieseffectsofpitandfissuresealantinthefirstpermanentmolarsofschoolagechildrenfromguangzhouapopulationbasedcohortstudy
AT liuweijia anticarieseffectsofpitandfissuresealantinthefirstpermanentmolarsofschoolagechildrenfromguangzhouapopulationbasedcohortstudy
AT xionglihua anticarieseffectsofpitandfissuresealantinthefirstpermanentmolarsofschoolagechildrenfromguangzhouapopulationbasedcohortstudy
AT lijianbo anticarieseffectsofpitandfissuresealantinthefirstpermanentmolarsofschoolagechildrenfromguangzhouapopulationbasedcohortstudy
AT guochongshan anticarieseffectsofpitandfissuresealantinthefirstpermanentmolarsofschoolagechildrenfromguangzhouapopulationbasedcohortstudy
AT fanweihua anticarieseffectsofpitandfissuresealantinthefirstpermanentmolarsofschoolagechildrenfromguangzhouapopulationbasedcohortstudy
AT huangshaohong anticarieseffectsofpitandfissuresealantinthefirstpermanentmolarsofschoolagechildrenfromguangzhouapopulationbasedcohortstudy