G-quadruplex ligand RHPS4 radiosensitizes glioblastoma xenograft in vivo through a differential targeting of bulky differentiated- and stem-cancer cells

BACKGROUND: Glioblastoma is the most aggressive and most lethal primary brain tumor in the adulthood. Current standard therapies are not curative and novel therapeutic options are urgently required. Present knowledge suggests that the continued glioblastoma growth and recurrence is determined by gli...

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Detalles Bibliográficos
Autores principales: Berardinelli, F., Tanori, M., Muoio, D., Buccarelli, M., di Masi, A., Leone, S., Ricci-Vitiani, L., Pallini, R., Mancuso, M., Antoccia, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636127/
https://www.ncbi.nlm.nih.gov/pubmed/31311580
http://dx.doi.org/10.1186/s13046-019-1293-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636127/
https://www.ncbi.nlm.nih.gov/pubmed/31311580
http://dx.doi.org/10.1186/s13046-019-1293-x

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