Somatic variants of potential clinical significance in the tumors of BRCA phenocopies

BACKGROUND: BRCA phenocopies are individuals with the same phenotype (i.e. cancer consistent with Hereditary Breast and Ovarian Cancer syndrome = HBOC) as their affected relatives, but not the same genotype as assessed by blood germline testing (i.e. they do not carry a germline BRCA1 or BRCA2 mutat...

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Detalles Bibliográficos
Autores principales: Buckingham, Lela, Mitchell, Rachel, Maienschein-Cline, Mark, Green, Stefan, Hu, Vincent Hong, Cobleigh, Melody, Rotmensch, Jacob, Burgess, Kelly, Usha, Lydia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636136/
https://www.ncbi.nlm.nih.gov/pubmed/31346352
http://dx.doi.org/10.1186/s13053-019-0117-5

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