HIV, immune activation and salt-sensitive hypertension (HISH): a research proposal

OBJECTIVE: The objective of this study is to quantify and compare the effect of excess dietary salt on immune cell activation and blood pressure in HIV versus HIV negative individuals. RESULTS: Salt-sensitivity is associated with increased immune cell activation in animal studies. This concept has n...

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Autores principales: Masenga, Sepiso K., Hamooya, Benson M., Nzala, Selestine, Kwenda, Geoffrey, Heimburger, Douglas C., Mutale, Wilbroad, Koethe, John R., Kirabo, Annet, Munsaka, Sody M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636142/
https://www.ncbi.nlm.nih.gov/pubmed/31311574
http://dx.doi.org/10.1186/s13104-019-4470-2
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author Masenga, Sepiso K.
Hamooya, Benson M.
Nzala, Selestine
Kwenda, Geoffrey
Heimburger, Douglas C.
Mutale, Wilbroad
Koethe, John R.
Kirabo, Annet
Munsaka, Sody M.
author_facet Masenga, Sepiso K.
Hamooya, Benson M.
Nzala, Selestine
Kwenda, Geoffrey
Heimburger, Douglas C.
Mutale, Wilbroad
Koethe, John R.
Kirabo, Annet
Munsaka, Sody M.
author_sort Masenga, Sepiso K.
collection PubMed
description OBJECTIVE: The objective of this study is to quantify and compare the effect of excess dietary salt on immune cell activation and blood pressure in HIV versus HIV negative individuals. RESULTS: Salt-sensitivity is associated with increased immune cell activation in animal studies. This concept has not been tested in people living with HIV. This study will therefore add more information in elucidating the interaction between HIV infection and/or anti-retroviral therapy (ART), immune-activation/inflammation and hypertension. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13104-019-4470-2) contains supplementary material, which is available to authorized users.
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spelling pubmed-66361422019-07-25 HIV, immune activation and salt-sensitive hypertension (HISH): a research proposal Masenga, Sepiso K. Hamooya, Benson M. Nzala, Selestine Kwenda, Geoffrey Heimburger, Douglas C. Mutale, Wilbroad Koethe, John R. Kirabo, Annet Munsaka, Sody M. BMC Res Notes Research Note OBJECTIVE: The objective of this study is to quantify and compare the effect of excess dietary salt on immune cell activation and blood pressure in HIV versus HIV negative individuals. RESULTS: Salt-sensitivity is associated with increased immune cell activation in animal studies. This concept has not been tested in people living with HIV. This study will therefore add more information in elucidating the interaction between HIV infection and/or anti-retroviral therapy (ART), immune-activation/inflammation and hypertension. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13104-019-4470-2) contains supplementary material, which is available to authorized users. BioMed Central 2019-07-16 /pmc/articles/PMC6636142/ /pubmed/31311574 http://dx.doi.org/10.1186/s13104-019-4470-2 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Note
Masenga, Sepiso K.
Hamooya, Benson M.
Nzala, Selestine
Kwenda, Geoffrey
Heimburger, Douglas C.
Mutale, Wilbroad
Koethe, John R.
Kirabo, Annet
Munsaka, Sody M.
HIV, immune activation and salt-sensitive hypertension (HISH): a research proposal
title HIV, immune activation and salt-sensitive hypertension (HISH): a research proposal
title_full HIV, immune activation and salt-sensitive hypertension (HISH): a research proposal
title_fullStr HIV, immune activation and salt-sensitive hypertension (HISH): a research proposal
title_full_unstemmed HIV, immune activation and salt-sensitive hypertension (HISH): a research proposal
title_short HIV, immune activation and salt-sensitive hypertension (HISH): a research proposal
title_sort hiv, immune activation and salt-sensitive hypertension (hish): a research proposal
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636142/
https://www.ncbi.nlm.nih.gov/pubmed/31311574
http://dx.doi.org/10.1186/s13104-019-4470-2
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