Functional DNA methylation signatures for autism spectrum disorder genomic risk loci: 16p11.2 deletions and CHD8 variants

BACKGROUND: Autism spectrum disorder (ASD) is a common and etiologically heterogeneous neurodevelopmental disorder. Although many genetic causes have been identified (> 200 ASD-risk genes), no single gene variant accounts for > 1% of all ASD cases. A role for epigenetic mechanisms in ASD etiol...

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Detalles Bibliográficos
Autores principales: Siu, M. T., Butcher, D. T., Turinsky, A. L., Cytrynbaum, C., Stavropoulos, D. J., Walker, S., Caluseriu, O., Carter, M., Lou, Y., Nicolson, R., Georgiades, S., Szatmari, P., Anagnostou, E., Scherer, S. W., Choufani, S., Brudno, M., Weksberg, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636171/
https://www.ncbi.nlm.nih.gov/pubmed/31311581
http://dx.doi.org/10.1186/s13148-019-0684-3

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