Anti-tumor Drug THZ1 Suppresses TGFβ2-mediated EMT in Lens Epithelial Cells via Notch and TGFβ/Smad Signaling Pathway

Selective covalent CDK7 inhibitor THZ1 is a promising potential anti-tumor drug in many kinds of cancers. Epithelial-mesenchymal Transition (EMT) is highly related to cancer initiation, development, invasion and metastasis and other pathogenesis processes. We treated cancer cell line Hela229 and thr...

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Detalles Bibliográficos
Autores principales: Ning, Jie, Ma, Xinqi, Long, Chongde, Mao, Yuxiang, Kuang, Xielan, Huang, Zixin, Fan, Yuting, Zhang, Han, Xia, Qing, Wang, Renchun, Liang, Yu, Lin, Shuibin, Zhang, Qingjiong, Shen, Huangxuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636287/
https://www.ncbi.nlm.nih.gov/pubmed/31333795
http://dx.doi.org/10.7150/jca.30359

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