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SIRT5 Promotes Hepatocellular Carcinoma Progression by Regulating Mitochondrial Apoptosis

SIRT5 belongs to a family of NAD(+)-dependent lysine deacetylases called sirtuins. Although accumulating evidence indicates SIRT5 upregulation in cancers, including liver cancer, the detailed roles and mechanisms remain to be revealed. Hepatocellular carcinoma (HCC) is the second leading cause of ca...

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Detalles Bibliográficos
Autores principales: Zhang, Rixin, Wang, Chengye, Tian, Yu, Yao, Yifan, Mao, Jiakai, Wang, Haibo, Li, Zhenghan, Xu, Yakun, Ye, Mingliang, Wang, Liming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636294/
https://www.ncbi.nlm.nih.gov/pubmed/31333804
http://dx.doi.org/10.7150/jca.31266