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PGC1α downregulation and glycolytic phenotype in thyroid cancer

Increased aerobic glycolysis portends an unfavorable prognosis in thyroid cancer. The metabolic reprogramming likely results from altered mitochondrial activity and may promote cancer progression. Peroxisome proliferator-activated receptor γ coactivator 1α (PGC1α) plays a pivotal role in mitochondri...

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Detalles Bibliográficos
Autores principales: Liu, Chien-Liang, Yang, Po-Sheng, Wang, Tao-Yeuan, Huang, Shih-Yuan, Kuo, Yi-Hue, Cheng, Shih-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636295/
https://www.ncbi.nlm.nih.gov/pubmed/31333799
http://dx.doi.org/10.7150/jca.30018

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