The role of Wnt signaling pathway in tumor metabolic reprogramming

The occurrence and development of tumors is a complex process involving long-term multi-factor participation. In this process, tumor cells from a set of abnormal metabolic patterns that are different from normal cells. This abnormal metabolic change is called metabolic reprogramming of tumors. Wnt s...

Descripción completa

Detalles Bibliográficos
Autores principales: Mo, Yongzhen, Wang, Yumin, Zhang, Lishen, Yang, Liting, Zhou, Ming, Li, Xiaoling, Li, Yong, Li, Guiyuan, Zeng, Zhaoyang, Xiong, Wei, Xiong, Fang, Guo, Can
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636296/
https://www.ncbi.nlm.nih.gov/pubmed/31333796
http://dx.doi.org/10.7150/jca.31166
_version_ 1783436039115767808
author Mo, Yongzhen
Wang, Yumin
Zhang, Lishen
Yang, Liting
Zhou, Ming
Li, Xiaoling
Li, Yong
Li, Guiyuan
Zeng, Zhaoyang
Xiong, Wei
Xiong, Fang
Guo, Can
author_facet Mo, Yongzhen
Wang, Yumin
Zhang, Lishen
Yang, Liting
Zhou, Ming
Li, Xiaoling
Li, Yong
Li, Guiyuan
Zeng, Zhaoyang
Xiong, Wei
Xiong, Fang
Guo, Can
author_sort Mo, Yongzhen
collection PubMed
description The occurrence and development of tumors is a complex process involving long-term multi-factor participation. In this process, tumor cells from a set of abnormal metabolic patterns that are different from normal cells. This abnormal metabolic change is called metabolic reprogramming of tumors. Wnt signaling pathway is one of the critical signaling pathways regulating cell proliferation and differentiation. In recent years, it has been found that Wnt signaling participates in the occurrence and development of malignant tumors by affecting metabolic reprogramming. This paper reviews the role of Wnt signaling in tumor metabolic reprogramming to provide crucial theoretical guidance for targeted therapy and drug response of tumors.
format Online
Article
Text
id pubmed-6636296
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Ivyspring International Publisher
record_format MEDLINE/PubMed
spelling pubmed-66362962019-07-22 The role of Wnt signaling pathway in tumor metabolic reprogramming Mo, Yongzhen Wang, Yumin Zhang, Lishen Yang, Liting Zhou, Ming Li, Xiaoling Li, Yong Li, Guiyuan Zeng, Zhaoyang Xiong, Wei Xiong, Fang Guo, Can J Cancer Review The occurrence and development of tumors is a complex process involving long-term multi-factor participation. In this process, tumor cells from a set of abnormal metabolic patterns that are different from normal cells. This abnormal metabolic change is called metabolic reprogramming of tumors. Wnt signaling pathway is one of the critical signaling pathways regulating cell proliferation and differentiation. In recent years, it has been found that Wnt signaling participates in the occurrence and development of malignant tumors by affecting metabolic reprogramming. This paper reviews the role of Wnt signaling in tumor metabolic reprogramming to provide crucial theoretical guidance for targeted therapy and drug response of tumors. Ivyspring International Publisher 2019-06-09 /pmc/articles/PMC6636296/ /pubmed/31333796 http://dx.doi.org/10.7150/jca.31166 Text en © Ivyspring International Publisher This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) license (https://creativecommons.org/licenses/by-nc/4.0/). See http://ivyspring.com/terms for full terms and conditions.
spellingShingle Review
Mo, Yongzhen
Wang, Yumin
Zhang, Lishen
Yang, Liting
Zhou, Ming
Li, Xiaoling
Li, Yong
Li, Guiyuan
Zeng, Zhaoyang
Xiong, Wei
Xiong, Fang
Guo, Can
The role of Wnt signaling pathway in tumor metabolic reprogramming
title The role of Wnt signaling pathway in tumor metabolic reprogramming
title_full The role of Wnt signaling pathway in tumor metabolic reprogramming
title_fullStr The role of Wnt signaling pathway in tumor metabolic reprogramming
title_full_unstemmed The role of Wnt signaling pathway in tumor metabolic reprogramming
title_short The role of Wnt signaling pathway in tumor metabolic reprogramming
title_sort role of wnt signaling pathway in tumor metabolic reprogramming
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636296/
https://www.ncbi.nlm.nih.gov/pubmed/31333796
http://dx.doi.org/10.7150/jca.31166
work_keys_str_mv AT moyongzhen theroleofwntsignalingpathwayintumormetabolicreprogramming
AT wangyumin theroleofwntsignalingpathwayintumormetabolicreprogramming
AT zhanglishen theroleofwntsignalingpathwayintumormetabolicreprogramming
AT yangliting theroleofwntsignalingpathwayintumormetabolicreprogramming
AT zhouming theroleofwntsignalingpathwayintumormetabolicreprogramming
AT lixiaoling theroleofwntsignalingpathwayintumormetabolicreprogramming
AT liyong theroleofwntsignalingpathwayintumormetabolicreprogramming
AT liguiyuan theroleofwntsignalingpathwayintumormetabolicreprogramming
AT zengzhaoyang theroleofwntsignalingpathwayintumormetabolicreprogramming
AT xiongwei theroleofwntsignalingpathwayintumormetabolicreprogramming
AT xiongfang theroleofwntsignalingpathwayintumormetabolicreprogramming
AT guocan theroleofwntsignalingpathwayintumormetabolicreprogramming
AT moyongzhen roleofwntsignalingpathwayintumormetabolicreprogramming
AT wangyumin roleofwntsignalingpathwayintumormetabolicreprogramming
AT zhanglishen roleofwntsignalingpathwayintumormetabolicreprogramming
AT yangliting roleofwntsignalingpathwayintumormetabolicreprogramming
AT zhouming roleofwntsignalingpathwayintumormetabolicreprogramming
AT lixiaoling roleofwntsignalingpathwayintumormetabolicreprogramming
AT liyong roleofwntsignalingpathwayintumormetabolicreprogramming
AT liguiyuan roleofwntsignalingpathwayintumormetabolicreprogramming
AT zengzhaoyang roleofwntsignalingpathwayintumormetabolicreprogramming
AT xiongwei roleofwntsignalingpathwayintumormetabolicreprogramming
AT xiongfang roleofwntsignalingpathwayintumormetabolicreprogramming
AT guocan roleofwntsignalingpathwayintumormetabolicreprogramming

Ejemplares similares