Cargando…

Co-delivery of everolimus and vinorelbine via a tumor-targeted liposomal formulation inhibits tumor growth and metastasis in RCC

BACKGROUND: Renal cell carcinoma (RCC) is notorious for its resistance towards chemotherapy and radiation therapy in general. Combination therapy is often helpful in alleviating the resistance mechanisms by targeting multiple signaling pathways but is usually more toxic than monotherapy. Co-encapsul...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pal, Krishnendu, Madamsetty, Vijay Sagar, Dutta, Shamit Kumar, Mukhopadhyay, Debabrata
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636461/ https://www.ncbi.nlm.nih.gov/pubmed/31371950 http://dx.doi.org/10.2147/IJN.S204221

Ejemplares similares

Synchronous inhibition of mTOR and VEGF/NRP1 axis impedes tumor growth and metastasis in renal cancer
por: Pal, Krishnendu, et al.
Publicado: (2019)

Targeted Dual Intervention-Oriented Drug-Encapsulated (DIODE) Nanoformulations for Improved Treatment of Pancreatic Cancer
por: Madamsetty, Vijay Sagar, et al.
Publicado: (2020)

VEGF neutralizing antibody increases the therapeutic efficacy of vinorelbine for renal cell carcinoma
por: Sinha, Sutapa, et al.
Publicado: (2010)

BRAF(V600E)-induced, tumor intrinsic PD-L1 can regulate chemotherapy-induced apoptosis in human colon cancer cells and in tumor xenografts
por: Feng, Daofu, et al.
Publicado: (2019)

Liposome Formulation for Tumor-Targeted Drug Delivery Using Radiation Therapy
por: Stolarz, Amanda J., et al.
Publicado: (2022)

LCC-09, a Novel Salicylanilide Derivative, Exerts Anti-Inflammatory Effect in Vascular Endothelial Cells
por: Angom, Ramcharan Singh, et al.
Publicado: (2021)

Safety and clinical efficacy of everolimus in the treatment of advanced renal cell carcinoma (RCC)
por: Shahani, Rohan, et al.
Publicado: (2010)

Preclinical efficacy of the novel competitive NAMPT inhibitor STF-118804 in pancreatic cancer
por: Espindola-Netto, Jair Machado, et al.
Publicado: (2017)

Role of PLEXIND1/TGFβ Signaling Axis in Pancreatic Ductal Adenocarcinoma Progression Correlates with the Mutational Status of KRAS
por: Vivekanandhan, Sneha, et al.
Publicado: (2021)

Formulation and Evaluation of Liposomes for Transdermal Delivery of Celecoxib
por: Moghimipour, Eskandar, et al.
Publicado: (2015)

Potent delivery of an MMP inhibitor to the tumor microenvironment with thermosensitive liposomes for the suppression of metastasis and angiogenesis
por: Lyu, Yaqi, et al.
Publicado: (2019)

Synergistic Antitumor Efficacy Mediated by Liposomal Co-Delivery of Polymeric Micelles of Vinorelbine and Cisplatin in Non-Small Cell Lung Cancer
por: Wang, Shuhang, et al.
Publicado: (2021)

The Contributions of HIF-Target Genes to Tumor Growth in RCC
por: Zhang, Ting, et al.
Publicado: (2013)

A Timely Oral Option: Single‐Agent Vinorelbine in Desmoid Tumors
por: Gennatas, Spyridon, et al.
Publicado: (2020)

Final overall survival analysis for the phase II RECORD-3 study of first-line everolimus followed by sunitinib versus first-line sunitinib followed by everolimus in metastatic RCC
por: Knox, J J, et al.
Publicado: (2018)

Final overall survival analysis for the phase II RECORD-3 study of first-line everolimus followed by sunitinib versus first-line sunitinib followed by everolimus in metastatic RCC
por: Knox, J. J., et al.
Publicado: (2017)

Tumor size, stage and grade alterations of urinary peptidome in RCC
por: Chinello, Clizia, et al.
Publicado: (2015)

Compare Fuhrman Nuclear and Chromophobe Tumor Grade on Chromophobe RCC
por: Lin, Tsu-Feng, et al.
Publicado: (2019)

Association of Circulating Tumor DNA (ctDNA) Detection in Metastatic Renal Cell Carcinoma (mRCC) with Tumor Burden
por: Maia, Manuel Caitano, et al.
Publicado: (2017)

Bioreducible Liposomes for Gene Delivery: From the Formulation to the Mechanism of Action
por: Candiani, Gabriele, et al.
Publicado: (2010)

Orally administered liposomal formulations for colon targeted drug delivery
por: Hua, Susan
Publicado: (2014)

Transcriptome-wide elucidation of liposomal formulations for anticancer drug delivery
por: Li, Ying, et al.
Publicado: (2017)

Topical Delivery of Meloxicam using Liposome and Microemulsion Formulation Approaches
por: Zhang, Julia, et al.
Publicado: (2020)

Systemic Protein Delivery via Inhalable Liposomes: Formulation and Pharmacokinetics
por: Ponkshe, Pranav, et al.
Publicado: (2023)

Recent Trends of the Bio-Inspired Nanoparticles in Cancer Theranostics
por: Madamsetty, Vijay Sagar, et al.
Publicado: (2019)

A multicenter prospective phase II randomized trial of epirubicin/vinorelbine versus pegylated liposomal doxorubicin/vinorelbine as first-line treatment in advanced breast cancer. A GOIM study
por: Vici, Patrizia, et al.
Publicado: (2011)

Evaluation of the in vivo genotoxicity of liposomal formulation for delivering anticancer estrogenic derivative (ESC8) in a mouse model
por: Ahmad, Ajaz, et al.
Publicado: (2019)

Emerging use of everolimus in the treatment of neuroendocrine tumors
por: Gajate, Pablo, et al.
Publicado: (2017)

Redox-sensitive doxorubicin liposome: a formulation approach for targeted tumor therapy
por: Mirhadi, Elaheh, et al.
Publicado: (2022)

Identification of RCC Subtype-Specific microRNAs–Meta-Analysis of High-Throughput RCC Tumor microRNA Expression Data
por: Kajdasz, Arkadiusz, et al.
Publicado: (2021)

New Horizons in Hydrogels for Methotrexate Delivery
por: Dehshahri, Ali, et al.
Publicado: (2020)

Combination of Everolimus with Sorafenib for Solid Renal Tumors in Tsc2(+/−) Mice Is Superior to Everolimus Alone()
por: Yang, Jian, et al.
Publicado: (2017)

Sialyl LewisX mimic-decorated liposomes for anti-angiogenic everolimus delivery to E-selectin expressing endothelial cells
por: Chantarasrivong, Chanikarn, et al.
Publicado: (2019)

A Comparison of Radiologic Tumor Volume and Pathologic Tumor Volume in Renal Cell Carcinoma (RCC)
por: Choi, See Min, et al.
Publicado: (2015)

Vorolanib and everolimus: Lenvatinib and everolimus part deux, or something new?
por: Chehrazi-Raffle, Alexander, et al.
Publicado: (2020)

Multifunctional targeting vinorelbine plus tetrandrine liposomes for treating brain glioma along with eliminating glioma stem cells
por: Li, Xue-tao, et al.
Publicado: (2016)

Antibody-modified liposomes for tumor-targeting delivery of timosaponin AIII
por: Lu, Lu, et al.
Publicado: (2018)

Liposome-Embedding Silicon Microparticle for Oxaliplatin Delivery in Tumor Chemotherapy
por: Cevenini, Armando, et al.
Publicado: (2020)

Liposomal flucytosine capped with gold nanoparticle formulations for improved ocular delivery
por: Salem, Heba F, et al.
Publicado: (2016)

Liposomal Formulations for Nose-to-Brain Delivery: Recent Advances and Future Perspectives
por: Hong, Soon-Seok, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_0v4jtg2816fg2rhant4cm5dc8t