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Predictive Model for the Risk of Severe Acute Malnutrition in Children
BACKGROUND: The nutritional status is the best indicator of the well-being of the child. Inadequate feeding practices are the main factors that affect physical growth and mental development. The aim of this study was to develop a predictive score of severe acute malnutrition (SAM) in children under...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636463/ https://www.ncbi.nlm.nih.gov/pubmed/31354989 http://dx.doi.org/10.1155/2019/4740825 |
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author | Mukuku, Olivier Mutombo, Augustin Mulangu Kamona, Lewis Kipili Lubala, Toni Kasole Mawaw, Paul Makan Aloni, Michel Ntetani Wembonyama, Stanislas Okitotsho Luboya, Oscar Numbi |
author_facet | Mukuku, Olivier Mutombo, Augustin Mulangu Kamona, Lewis Kipili Lubala, Toni Kasole Mawaw, Paul Makan Aloni, Michel Ntetani Wembonyama, Stanislas Okitotsho Luboya, Oscar Numbi |
author_sort | Mukuku, Olivier |
collection | PubMed |
description | BACKGROUND: The nutritional status is the best indicator of the well-being of the child. Inadequate feeding practices are the main factors that affect physical growth and mental development. The aim of this study was to develop a predictive score of severe acute malnutrition (SAM) in children under 5 years of age. METHODS: It was a case-control study. The case group (n = 263) consisted of children aged 6 to 59 months admitted to hospital for SAM that was defined by a z-score weight/height < −3 SD or presence of edema of malnutrition. We performed a univariate and multivariate analysis. Discrimination score was assessed using the ROC curve and the calibration of the score by Hosmer–Lemeshow test. RESULTS: Low birth weight, history of recurrent or chronic diarrhea, daily meal's number less than 3, age of breastfeeding's cessation less than 6 months, age of introduction of complementary diets less than 6 months, maternal age below 25 years, parity less than 5, family history of malnutrition, and number of children under 5 over 2 were predictive factors of SAM. Presence of these nine criteria affects a certain number of points; a score <6 points defines children at low risk of SAM, a score between 6 and 8 points defines a moderate risk of SAM, and a score >8 points presents a high risk of SAM. The area under ROC curve of this score was 0.9685, its sensitivity was 93.5%, and its specificity was 93.1%. CONCLUSION: We propose a simple and efficient prediction model for the risk of occurrence of SAM in children under 5 years of age in developing countries. This predictive model of SAM would be a useful and simple clinical tool to identify people at risk, limit high rates of malnutrition, and reduce disease and child mortality registered in developing countries. |
format | Online Article Text |
id | pubmed-6636463 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-66364632019-07-28 Predictive Model for the Risk of Severe Acute Malnutrition in Children Mukuku, Olivier Mutombo, Augustin Mulangu Kamona, Lewis Kipili Lubala, Toni Kasole Mawaw, Paul Makan Aloni, Michel Ntetani Wembonyama, Stanislas Okitotsho Luboya, Oscar Numbi J Nutr Metab Research Article BACKGROUND: The nutritional status is the best indicator of the well-being of the child. Inadequate feeding practices are the main factors that affect physical growth and mental development. The aim of this study was to develop a predictive score of severe acute malnutrition (SAM) in children under 5 years of age. METHODS: It was a case-control study. The case group (n = 263) consisted of children aged 6 to 59 months admitted to hospital for SAM that was defined by a z-score weight/height < −3 SD or presence of edema of malnutrition. We performed a univariate and multivariate analysis. Discrimination score was assessed using the ROC curve and the calibration of the score by Hosmer–Lemeshow test. RESULTS: Low birth weight, history of recurrent or chronic diarrhea, daily meal's number less than 3, age of breastfeeding's cessation less than 6 months, age of introduction of complementary diets less than 6 months, maternal age below 25 years, parity less than 5, family history of malnutrition, and number of children under 5 over 2 were predictive factors of SAM. Presence of these nine criteria affects a certain number of points; a score <6 points defines children at low risk of SAM, a score between 6 and 8 points defines a moderate risk of SAM, and a score >8 points presents a high risk of SAM. The area under ROC curve of this score was 0.9685, its sensitivity was 93.5%, and its specificity was 93.1%. CONCLUSION: We propose a simple and efficient prediction model for the risk of occurrence of SAM in children under 5 years of age in developing countries. This predictive model of SAM would be a useful and simple clinical tool to identify people at risk, limit high rates of malnutrition, and reduce disease and child mortality registered in developing countries. Hindawi 2019-07-01 /pmc/articles/PMC6636463/ /pubmed/31354989 http://dx.doi.org/10.1155/2019/4740825 Text en Copyright © 2019 Olivier Mukuku et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Mukuku, Olivier Mutombo, Augustin Mulangu Kamona, Lewis Kipili Lubala, Toni Kasole Mawaw, Paul Makan Aloni, Michel Ntetani Wembonyama, Stanislas Okitotsho Luboya, Oscar Numbi Predictive Model for the Risk of Severe Acute Malnutrition in Children |
title | Predictive Model for the Risk of Severe Acute Malnutrition in Children |
title_full | Predictive Model for the Risk of Severe Acute Malnutrition in Children |
title_fullStr | Predictive Model for the Risk of Severe Acute Malnutrition in Children |
title_full_unstemmed | Predictive Model for the Risk of Severe Acute Malnutrition in Children |
title_short | Predictive Model for the Risk of Severe Acute Malnutrition in Children |
title_sort | predictive model for the risk of severe acute malnutrition in children |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636463/ https://www.ncbi.nlm.nih.gov/pubmed/31354989 http://dx.doi.org/10.1155/2019/4740825 |
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