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Predictive Model for the Risk of Severe Acute Malnutrition in Children

BACKGROUND: The nutritional status is the best indicator of the well-being of the child. Inadequate feeding practices are the main factors that affect physical growth and mental development. The aim of this study was to develop a predictive score of severe acute malnutrition (SAM) in children under...

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Autores principales: Mukuku, Olivier, Mutombo, Augustin Mulangu, Kamona, Lewis Kipili, Lubala, Toni Kasole, Mawaw, Paul Makan, Aloni, Michel Ntetani, Wembonyama, Stanislas Okitotsho, Luboya, Oscar Numbi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636463/
https://www.ncbi.nlm.nih.gov/pubmed/31354989
http://dx.doi.org/10.1155/2019/4740825
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author Mukuku, Olivier
Mutombo, Augustin Mulangu
Kamona, Lewis Kipili
Lubala, Toni Kasole
Mawaw, Paul Makan
Aloni, Michel Ntetani
Wembonyama, Stanislas Okitotsho
Luboya, Oscar Numbi
author_facet Mukuku, Olivier
Mutombo, Augustin Mulangu
Kamona, Lewis Kipili
Lubala, Toni Kasole
Mawaw, Paul Makan
Aloni, Michel Ntetani
Wembonyama, Stanislas Okitotsho
Luboya, Oscar Numbi
author_sort Mukuku, Olivier
collection PubMed
description BACKGROUND: The nutritional status is the best indicator of the well-being of the child. Inadequate feeding practices are the main factors that affect physical growth and mental development. The aim of this study was to develop a predictive score of severe acute malnutrition (SAM) in children under 5 years of age. METHODS: It was a case-control study. The case group (n = 263) consisted of children aged 6 to 59 months admitted to hospital for SAM that was defined by a z-score weight/height < −3 SD or presence of edema of malnutrition. We performed a univariate and multivariate analysis. Discrimination score was assessed using the ROC curve and the calibration of the score by Hosmer–Lemeshow test. RESULTS: Low birth weight, history of recurrent or chronic diarrhea, daily meal's number less than 3, age of breastfeeding's cessation less than 6 months, age of introduction of complementary diets less than 6 months, maternal age below 25 years, parity less than 5, family history of malnutrition, and number of children under 5 over 2 were predictive factors of SAM. Presence of these nine criteria affects a certain number of points; a score <6 points defines children at low risk of SAM, a score between 6 and 8 points defines a moderate risk of SAM, and a score >8 points presents a high risk of SAM. The area under ROC curve of this score was 0.9685, its sensitivity was 93.5%, and its specificity was 93.1%. CONCLUSION: We propose a simple and efficient prediction model for the risk of occurrence of SAM in children under 5 years of age in developing countries. This predictive model of SAM would be a useful and simple clinical tool to identify people at risk, limit high rates of malnutrition, and reduce disease and child mortality registered in developing countries.
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spelling pubmed-66364632019-07-28 Predictive Model for the Risk of Severe Acute Malnutrition in Children Mukuku, Olivier Mutombo, Augustin Mulangu Kamona, Lewis Kipili Lubala, Toni Kasole Mawaw, Paul Makan Aloni, Michel Ntetani Wembonyama, Stanislas Okitotsho Luboya, Oscar Numbi J Nutr Metab Research Article BACKGROUND: The nutritional status is the best indicator of the well-being of the child. Inadequate feeding practices are the main factors that affect physical growth and mental development. The aim of this study was to develop a predictive score of severe acute malnutrition (SAM) in children under 5 years of age. METHODS: It was a case-control study. The case group (n = 263) consisted of children aged 6 to 59 months admitted to hospital for SAM that was defined by a z-score weight/height < −3 SD or presence of edema of malnutrition. We performed a univariate and multivariate analysis. Discrimination score was assessed using the ROC curve and the calibration of the score by Hosmer–Lemeshow test. RESULTS: Low birth weight, history of recurrent or chronic diarrhea, daily meal's number less than 3, age of breastfeeding's cessation less than 6 months, age of introduction of complementary diets less than 6 months, maternal age below 25 years, parity less than 5, family history of malnutrition, and number of children under 5 over 2 were predictive factors of SAM. Presence of these nine criteria affects a certain number of points; a score <6 points defines children at low risk of SAM, a score between 6 and 8 points defines a moderate risk of SAM, and a score >8 points presents a high risk of SAM. The area under ROC curve of this score was 0.9685, its sensitivity was 93.5%, and its specificity was 93.1%. CONCLUSION: We propose a simple and efficient prediction model for the risk of occurrence of SAM in children under 5 years of age in developing countries. This predictive model of SAM would be a useful and simple clinical tool to identify people at risk, limit high rates of malnutrition, and reduce disease and child mortality registered in developing countries. Hindawi 2019-07-01 /pmc/articles/PMC6636463/ /pubmed/31354989 http://dx.doi.org/10.1155/2019/4740825 Text en Copyright © 2019 Olivier Mukuku et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Mukuku, Olivier
Mutombo, Augustin Mulangu
Kamona, Lewis Kipili
Lubala, Toni Kasole
Mawaw, Paul Makan
Aloni, Michel Ntetani
Wembonyama, Stanislas Okitotsho
Luboya, Oscar Numbi
Predictive Model for the Risk of Severe Acute Malnutrition in Children
title Predictive Model for the Risk of Severe Acute Malnutrition in Children
title_full Predictive Model for the Risk of Severe Acute Malnutrition in Children
title_fullStr Predictive Model for the Risk of Severe Acute Malnutrition in Children
title_full_unstemmed Predictive Model for the Risk of Severe Acute Malnutrition in Children
title_short Predictive Model for the Risk of Severe Acute Malnutrition in Children
title_sort predictive model for the risk of severe acute malnutrition in children
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636463/
https://www.ncbi.nlm.nih.gov/pubmed/31354989
http://dx.doi.org/10.1155/2019/4740825
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