Cargando…

Bailcalin Protects against Diabetic Cardiomyopathy through Keap1/Nrf2/AMPK-Mediated Antioxidative and Lipid-Lowering Effects

Previous studies demonstrated that Bailcalin (BAI) prevented cardiac injuries under different disease models. Whether BAI protected against type 2 diabetes mellitus- (T2DM-) associated cardiomyopathy was investigated in this study. T2DM was established by the combination of streptozotocin injection...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Ran, Liu, Yuan, Shan, Ying-guang, Gao, Lu, Wang, Fang, Qiu, Chun-guang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636513/ https://www.ncbi.nlm.nih.gov/pubmed/31354905 http://dx.doi.org/10.1155/2019/3206542

Ejemplares similares

Resveratrol protects against oxidative stress by activating the Keap-1/Nrf2 antioxidant defense system in obese-asthmatic rats
por: Li, Xiao-Nan, et al.
Publicado: (2018)

Signal amplification in the KEAP1-NRF2-ARE antioxidant response pathway
por: Liu, Shengnan, et al.
Publicado: (2022)

Fibroblast growth factor-21 prevents diabetic cardiomyopathy via AMPK-mediated antioxidation and lipid-lowering effects in the heart
por: Yang, Hong, et al.
Publicado: (2018)

Trehalose protects against oxidative stress by regulating the Keap1–Nrf2 and autophagy pathways
por: Mizunoe, Yuhei, et al.
Publicado: (2017)

Diosmetin Protects against Cardiac Hypertrophy via p62/Keap1/Nrf2 Signaling Pathway
por: Guo, Yingying, et al.
Publicado: (2022)

Cyclovirobuxine D protects against diabetic cardiomyopathy by activating Nrf2-mediated antioxidant responses
por: Jiang, Zhaohui, et al.
Publicado: (2020)

Pharmacological Protection against Ischemia-Reperfusion Injury by Regulating the Nrf2-Keap1-ARE Signaling Pathway
por: Ucar, Bercis Imge, et al.
Publicado: (2021)

Role of Keap1-Nrf2/ARE signal transduction pathway in protection of dexmedetomidine preconditioning against myocardial ischemia/reperfusion injury
por: Li, Hui-xian, et al.
Publicado: (2022)

Polysaccharides from Hemp Seed Protect against Cyclophosphamide-Induced Intestinal Oxidative Damage via Nrf2-Keap1 Signaling Pathway in Mice
por: Xue, Ran, et al.
Publicado: (2020)

Phloretin Prevents Diabetic Cardiomyopathy by Dissociating Keap1/Nrf2 Complex and Inhibiting Oxidative Stress
por: Ying, Yin, et al.
Publicado: (2018)

Protection against oxidative stress mediated by the Nrf2/Keap1 axis is impaired in Primary Biliary Cholangitis
por: Wasik, Urszula, et al.
Publicado: (2017)

FAM129B, an antioxidative protein, reduces chemosensitivity by competing with Nrf2 for Keap1 binding
por: Cheng, Kai-Chun, et al.
Publicado: (2019)

Tsg101 positively regulates P62-Keap1-Nrf2 pathway to protect hearts against oxidative damage
por: Deng, Shan, et al.
Publicado: (2020)

The KEAP1–NRF2 System in Cancer
por: Taguchi, Keiko, et al.
Publicado: (2017)

Keap1/Nrf2 Signaling Pathway
por: Sykiotis, Gerasimos P.
Publicado: (2021)

Antioxidant axis Nrf2-keap1-ARE in inhibition of alcoholic liver fibrosis by IL-22
por: Ni, Ya-Hui, et al.
Publicado: (2017)

Honey and Chamomile Activate Keratinocyte Antioxidative Responses via the KEAP1/NRF2 System
por: Ogawa, Tatsuya, et al.
Publicado: (2020)

A Bibliometric Review of the Keap1/Nrf2 Pathway and its Related Antioxidant Compounds
por: Paunkov, Ana, et al.
Publicado: (2019)

Chaperone‐mediated autophagy degrades Keap1 and promotes Nrf2‐mediated antioxidative response
por: Zhu, Lin, et al.
Publicado: (2022)

Beyond Antioxidation: Keap1–Nrf2 in the Development and Effector Functions of Adaptive Immune Cells
por: Pant, Anil, et al.
Publicado: (2023)

Catalpol Protects ARPE-19 Cells against Oxidative Stress via Activation of the Keap1/Nrf2/ARE Pathway
por: You, Longtai, et al.
Publicado: (2021)

Activation of the P62-Keap1-NRF2 Pathway Protects against Ferroptosis in Radiation-Induced Lung Injury
por: Li, Xuan, et al.
Publicado: (2022)

MK-886 protects against cardiac ischaemia/reperfusion injury by activating proteasome-Keap1-NRF2 signalling
por: Shi, Kai-Na, et al.
Publicado: (2023)

Curcumin protects against doxorubicin induced oxidative stress by regulating the Keap1-Nrf2-ARE and autophagy signaling pathways
por: Liao, Dehua, et al.
Publicado: (2023)

Identification of a novel small-molecule Keap1–Nrf2 PPI inhibitor with cytoprotective effects on LPS-induced cardiomyopathy
por: Jiang, Cheng-Shi, et al.
Publicado: (2018)

Antioxidant, Lipid Lowering, and Membrane Stabilization Effect of Sesamol against Doxorubicin-Induced Cardiomyopathy in Experimental Rats
por: Chennuru, Anusha, et al.
Publicado: (2013)

Protein kinase CK2 activates Nrf2 via autophagic degradation of Keap1 and activation of AMPK in human cancer cells
por: Jang, Da Eun, et al.
Publicado: (2020)

Structural basis of Keap1 interactions with Nrf2
por: Canning, Peter, et al.
Publicado: (2015)

Epigenetic Regulation of NRF2/KEAP1 by Phytochemicals
por: Bhattacharjee, Shamee, et al.
Publicado: (2020)

The KEAP1/NRF2 Signaling Pathway in Keratinization
por: Ishitsuka, Yosuke, et al.
Publicado: (2020)

The KEAP1-NRF2 System and Esophageal Cancer
por: Hirose, Wataru, et al.
Publicado: (2022)

Modulation of NRF2/KEAP1 Signaling in Preeclampsia
por: Tossetta, Giovanni, et al.
Publicado: (2023)

The Role of NRF2/KEAP1 Signaling Pathway in Cancer Metabolism
por: Song, Moon-Young, et al.
Publicado: (2021)

Impaired antioxidant KEAP1-NRF2 system in amyotrophic lateral sclerosis: NRF2 activation as a potential therapeutic strategy
por: Bono, Silvia, et al.
Publicado: (2021)

Dietary resveratrol improves antioxidant status of sows and piglets and regulates antioxidant gene expression in placenta by Keap1-Nrf2 pathway and Sirt1
por: Meng, Qingwei, et al.
Publicado: (2018)

Schisandrin B protects against angiotensin II-induced endotheliocyte deficits by targeting Keap1 and activating Nrf2 pathway
por: Han, Jibo, et al.
Publicado: (2018)

Puerarin protects against acetaminophen‐induced oxidative damage in liver through activation of the Keap1/Nrf2 signaling pathway
por: Zhou, Wanhai, et al.
Publicado: (2023)

A Protective Role of the NRF2-Keap1 Pathway in Maintaining Intestinal Barrier Function
por: Wen, Zhiyong, et al.
Publicado: (2019)

Ferroptosis is essential for diabetic cardiomyopathy and is prevented by sulforaphane via AMPK/NRF2 pathways
por: Wang, Xiang, et al.
Publicado: (2022)

Nrf2/Keap1/ARE Signaling Mediated an Antioxidative Protection of Human Placental Mesenchymal Stem Cells of Fetal Origin in Alveolar Epithelial Cells
por: Yan, Xiurui, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_7v7oau8lqjenkic4h7oin93kko