Cargando…

Therapeutic Effect of the Mitochondria-Targeted Antioxidant SkQ1 on the Culture Model of Multiple Sclerosis

Multiple sclerosis (MS) is a heterogeneous autoimmune disease of unknown etiology characterized by inflammation, demyelination, and axonal degeneration that affects both the white and gray matter of CNS. Recent large-scale epidemiological and genomic studies identified several genetic and environmen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fetisova, Elena K., Muntyan, Maria S., Lyamzaev, Konstantin G., Chernyak, Boris V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636568/ https://www.ncbi.nlm.nih.gov/pubmed/31354902 http://dx.doi.org/10.1155/2019/2082561

Ejemplares similares

Effects of the mitochondria-targeted antioxidant SkQ1 on lifespan of rodents
por: Anisimov, Vladimir N., et al.
Publicado: (2011)

Mitochondria-targeted antioxidant SkQ1 inhibits leukotriene synthesis in human neutrophils
por: Sud’ina, Galina F., et al.
Publicado: (2022)

Mitochondria-Targeted Antioxidant SkQ1 Improves Dermal Wound Healing in Genetically Diabetic Mice
por: Demyanenko, Ilya A., et al.
Publicado: (2017)

Mitochondria-targeted antioxidant SkQ1 improves impaired dermal wound healing in old mice
por: Demyanenko, Ilya A., et al.
Publicado: (2015)

The Analgesic Effect of the Mitochondria-Targeted Antioxidant SkQ1 in Pancreatic Inflammation
por: Weniger, Maximilian, et al.
Publicado: (2016)

Mitochondria-Targeted Antioxidant SkQ1 Prevents the Development of Experimental Colitis in Mice and Impairment of the Barrier Function of the Intestinal Epithelium
por: Fedorov, Artem V., et al.
Publicado: (2022)

Mitochondrion-targeted antioxidant SkQ1 prevents rapid animal death caused by highly diverse shocks
por: Skulachev, V. P., et al.
Publicado: (2023)

Mitochondria-Targeted Antioxidant SkQ1 Prevents Anesthesia-Induced Dry Eye Syndrome
por: Zernii, Evgeni Yu., et al.
Publicado: (2017)

The mitochondria-targeted antioxidant SkQ1 but not N-acetylcysteine reverses aging-related biomarkers in rats
por: Kolosova, Nataliya G., et al.
Publicado: (2012)

Mitochondria-targeted antioxidant SkQ1 reduces age-related alterations in the ultrastructure of the lacrimal gland
por: Bakeeva, Lora E., et al.
Publicado: (2016)

Mitochondrial antioxidant SkQ1 decreases inflammation following hemorrhagic shock by protecting myocardial mitochondria
por: Jia, Bo, et al.
Publicado: (2022)

Antioxidant SkQ1 delays sarcopenia-associated damage of mitochondrial ultrastructure
por: Vays, Valeriya B., et al.
Publicado: (2014)

Therapeutic Action of the Mitochondria-Targeted Antioxidant SkQ1 on Retinopathy in OXYS Rats Linked with Improvement of VEGF and PEDF Gene Expression
por: Markovets, Anton M., et al.
Publicado: (2011)

Mitochondria-targeted antioxidant SkQ1 inhibits age-dependent involution of the thymus in normal and senescence-prone rats
por: Obukhova, Lidia A., et al.
Publicado: (2009)

Suppression of Alzheimer's Disease-Like Pathology Progression by Mitochondria-Targeted Antioxidant SkQ1: A Transcriptome Profiling Study
por: Stefanova, Natalia A., et al.
Publicado: (2019)

Changes in Glial Support of the Hippocampus during the Development of an Alzheimer’s Disease-like Pathology and Their Correction by Mitochondria-Targeted Antioxidant SkQ1
por: Rudnitskaya, Ekaterina A., et al.
Publicado: (2022)

Treating Neurodegenerative Disease with Antioxidants: Efficacy of the Bioactive Phenol Resveratrol and Mitochondrial-Targeted MitoQ and SkQ
por: Shinn, Lindsey J., et al.
Publicado: (2021)

Current perspectives of mitochondria-targeted antioxidants in cancer prevention and treatment
por: Zinovkin, Roman A., et al.
Publicado: (2023)

The Mitochondria-Targeted Antioxidant SkQ1 Downregulates Aryl Hydrocarbon Receptor-Dependent Genes in the Retina of OXYS Rats with AMD-Like Retinopathy
por: Perepechaeva, M. L., et al.
Publicado: (2014)

Mitochondria-Targeted Antioxidants SkQ1 and MitoTEMPO Failed to Exert a Long-Term Beneficial Effect in Murine Polymicrobial Sepsis
por: Rademann, Pia, et al.
Publicado: (2017)

Suppression of AMD-Like Pathology by Mitochondria-Targeted Antioxidant SkQ1 Is Associated with a Decrease in the Accumulation of Amyloid β and in mTOR Activity
por: Muraleva, Natalia A., et al.
Publicado: (2019)

Efficacy of Mitochondrial Antioxidant Plastoquinonyl-decyl-triphenylphosphonium Bromide (SkQ1) in the Rat Model of Autoimmune Arthritis
por: Andreev-Andrievskiy, Alexander A., et al.
Publicado: (2016)

Improved health-span and lifespan in mtDNA mutator mice treated with the mitochondrially targeted antioxidant SkQ1
por: Shabalina, Irina G., et al.
Publicado: (2017)

SkQ1 treatment and food restriction — two ways to retard an aging program of organisms
por: Skulachev, Vladimir P.
Publicado: (2011)

SkQ1 Suppresses the p38 MAPK Signaling Pathway Involved in Alzheimer’s Disease-Like Pathology in OXYS Rats
por: Muraleva, Natalia A., et al.
Publicado: (2020)

Mitochondria as Targets for Endothelial Protection in COVID-19
por: Chernyak, Boris V., et al.
Publicado: (2020)

The Role of SKQ1 (Visomitin) in Inflammation and Wound Healing of the Ocular Surface
por: Wei, Yi, et al.
Publicado: (2018)

Mitochondrial Antioxidant SkQ1 Has a Beneficial Effect in Experimental Diabetes as Based on the Analysis of Expression of microRNAs and mRNAs for the Oxidative Metabolism Regulators
por: Dvoretskaya, Yuliya, et al.
Publicado: (2021)

Genetic Variability of the AcrAB-TolC Multidrug Efflux Pump Underlies SkQ1 Resistance in Gram-Negative Bacteria
por: Nazarov, P. A., et al.
Publicado: (2019)

Innate Immunity and Phenoptosis
por: Chernyak, Boris V., et al.
Publicado: (2023)

Mitochondria-targeted antioxidant SKQ1 protects cornea from oxidative damage induced by ultraviolet irradiation and mechanical injury
por: Zernii, Evgeni Yu., et al.
Publicado: (2018)

Innate Immunity as an Executor of the Programmed Death of Individual Organisms for the Benefit of the Entire Population
por: Chernyak, Boris V., et al.
Publicado: (2021)

MitoCLox: A Novel Mitochondria-Targeted Fluorescent Probe for Tracing Lipid Peroxidation
por: Lyamzaev, Konstantin G., et al.
Publicado: (2019)

SkQ1 Ophthalmic Solution for Dry Eye Treatment: Results of a Phase 2 Safety and Efficacy Clinical Study in the Environment and During Challenge in the Controlled Adverse Environment Model
por: Petrov, Anton, et al.
Publicado: (2016)

Mitochondria-targeted antioxidants as highly effective antibiotics
por: Nazarov, Pavel A., et al.
Publicado: (2017)

Mitochondrial Targeted Antioxidant SKQ1 Ameliorates Acute Kidney Injury by Inhibiting Ferroptosis
por: Song, Jiayu, et al.
Publicado: (2022)

Novel Fluorescent Mitochondria-Targeted Probe MitoCLox Reports Lipid Peroxidation in Response to Oxidative Stress In Vivo
por: Lyamzaev, Konstantin G., et al.
Publicado: (2020)

Six Functions of Respiration: Isn’t It Time to Take Control over ROS Production in Mitochondria, and Aging Along with It?
por: Skulachev, Vladimir P., et al.
Publicado: (2023)

Mitochondrial Lipid Peroxidation Is Responsible for Ferroptosis
por: Lyamzaev, Konstantin G., et al.
Publicado: (2023)

Ordered Clusters of the Complete Oxidative Phosphorylation System in Cardiac Mitochondria
por: Nesterov, Semen, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_outdesq1qajlckm0f9v3e21noa