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The quantity of CD40 signaling determines the differentiation of B cells into functionally distinct memory cell subsets
In mice, memory B (B(mem)) cells can be divided into two subpopulations: CD80(hi) B(mem) cells, which preferentially differentiate into plasma cells; and CD80(lo) B(mem) cells, which become germinal center (GC) B cells during a recall response. We demonstrate that these distinct responses can be B-c...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636905/ https://www.ncbi.nlm.nih.gov/pubmed/31225793 http://dx.doi.org/10.7554/eLife.44245 |