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Protein lysine de-2-hydroxyisobutyrylation by CobB in prokaryotes
Lysine 2-hydroxyisobutyrylation (Khib) has recently been shown to be an evolutionarily conserved histone mark. Here, we report that CobB serves as a lysine de-2-hydroxyisobutyrylation enzyme that regulates glycolysis and cell growth in prokaryotes. We identified the specific binding of CobB to Khib...
Autores principales: | Dong, Hanyang, Zhai, Guijin, Chen, Cong, Bai, Xue, Tian, Shanshan, Hu, Deqing, Fan, Enguo, Zhang, Kai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636992/ https://www.ncbi.nlm.nih.gov/pubmed/31328167 http://dx.doi.org/10.1126/sciadv.aaw6703 |
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