Fc receptor–like 1 intrinsically recruits c-Abl to enhance B cell activation and function

B cell activation is regulated by the stimulatory or inhibitory co-receptors of B cell receptors (BCRs). Here, we investigated the signaling mechanism of Fc receptor-like 1 (FcRL1), a newly identified BCR co-receptor. FcRL1 was passively recruited into B cell immunological synapses upon BCR engageme...

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Detalles Bibliográficos
Autores principales: Zhao, Xingwang, Xie, Hengyi, Zhao, Meng, Ahsan, Asma, Li, Xinxin, Wang, Fei, Yi, Junyang, Yang, Zhiyong, Wu, Chuan, Raman, Indu, Li, Quan-Zhen, Kim, Tae Jin, Liu, Wanli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637015/
https://www.ncbi.nlm.nih.gov/pubmed/31328160
http://dx.doi.org/10.1126/sciadv.aaw0315

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