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Outcomes of Intrathecal Baclofen Therapy Compared With Deep Brain Stimulation in a Patient With Dystonic Cerebral Palsy: A Case Report

Deep brain stimulation (DBS) in internal globus pallidus is considered to be a good option for controlling generalized dystonia in patients with this condition. In this relation, it is known that DBS has already been shown to have significant effects on primary dystonia, but is seen as controversial...

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Autores principales: Chae, Minji, Hong, Seungbeen, Jung, Na Young, Chang, Won Seok, Cho, Sung-Rae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Academy of Rehabilitation Medicine 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637060/
https://www.ncbi.nlm.nih.gov/pubmed/31311256
http://dx.doi.org/10.5535/arm.2019.43.3.335
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author Chae, Minji
Hong, Seungbeen
Jung, Na Young
Chang, Won Seok
Cho, Sung-Rae
author_facet Chae, Minji
Hong, Seungbeen
Jung, Na Young
Chang, Won Seok
Cho, Sung-Rae
author_sort Chae, Minji
collection PubMed
description Deep brain stimulation (DBS) in internal globus pallidus is considered to be a good option for controlling generalized dystonia in patients with this condition. In this relation, it is known that DBS has already been shown to have significant effects on primary dystonia, but is seen as controversial in secondary dystonia including cerebral palsy (CP). On the other hand, intrathecal baclofen (ITB) has been known to reduce spasticity and dystonia in patients who did not respond to oral medications or botulinum toxin treatment. Here, we report a patient with dystonic CP, who received the ITB pump implantation long after the DBS and who noted remarkable improvement in the 36-Item Short Form Health Survey, Dystonia Rating Scale, Modified Barthel Index, and visual analog scale scores for pain after an ITB pump implantation was used as compared with DBS. To our knowledge, the present case report is the first to demonstrate the effects of an ITB pump on reducing pain and dystonia and improving quality of life and satisfaction, compared with DBS in a patient with CP.
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spelling pubmed-66370602019-07-26 Outcomes of Intrathecal Baclofen Therapy Compared With Deep Brain Stimulation in a Patient With Dystonic Cerebral Palsy: A Case Report Chae, Minji Hong, Seungbeen Jung, Na Young Chang, Won Seok Cho, Sung-Rae Ann Rehabil Med Case Report Deep brain stimulation (DBS) in internal globus pallidus is considered to be a good option for controlling generalized dystonia in patients with this condition. In this relation, it is known that DBS has already been shown to have significant effects on primary dystonia, but is seen as controversial in secondary dystonia including cerebral palsy (CP). On the other hand, intrathecal baclofen (ITB) has been known to reduce spasticity and dystonia in patients who did not respond to oral medications or botulinum toxin treatment. Here, we report a patient with dystonic CP, who received the ITB pump implantation long after the DBS and who noted remarkable improvement in the 36-Item Short Form Health Survey, Dystonia Rating Scale, Modified Barthel Index, and visual analog scale scores for pain after an ITB pump implantation was used as compared with DBS. To our knowledge, the present case report is the first to demonstrate the effects of an ITB pump on reducing pain and dystonia and improving quality of life and satisfaction, compared with DBS in a patient with CP. Korean Academy of Rehabilitation Medicine 2019-06 2019-06-28 /pmc/articles/PMC6637060/ /pubmed/31311256 http://dx.doi.org/10.5535/arm.2019.43.3.335 Text en Copyright © 2019 by Korean Academy of Rehabilitation Medicine This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Chae, Minji
Hong, Seungbeen
Jung, Na Young
Chang, Won Seok
Cho, Sung-Rae
Outcomes of Intrathecal Baclofen Therapy Compared With Deep Brain Stimulation in a Patient With Dystonic Cerebral Palsy: A Case Report
title Outcomes of Intrathecal Baclofen Therapy Compared With Deep Brain Stimulation in a Patient With Dystonic Cerebral Palsy: A Case Report
title_full Outcomes of Intrathecal Baclofen Therapy Compared With Deep Brain Stimulation in a Patient With Dystonic Cerebral Palsy: A Case Report
title_fullStr Outcomes of Intrathecal Baclofen Therapy Compared With Deep Brain Stimulation in a Patient With Dystonic Cerebral Palsy: A Case Report
title_full_unstemmed Outcomes of Intrathecal Baclofen Therapy Compared With Deep Brain Stimulation in a Patient With Dystonic Cerebral Palsy: A Case Report
title_short Outcomes of Intrathecal Baclofen Therapy Compared With Deep Brain Stimulation in a Patient With Dystonic Cerebral Palsy: A Case Report
title_sort outcomes of intrathecal baclofen therapy compared with deep brain stimulation in a patient with dystonic cerebral palsy: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637060/
https://www.ncbi.nlm.nih.gov/pubmed/31311256
http://dx.doi.org/10.5535/arm.2019.43.3.335
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