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Chiral phosphoric acid catalyzed aminative dearomatization of α-naphthols/Michael addition sequence

Asymmetric dearomatization reactions have recently emerged as a powerful tool for the rapid build-up of the molecular complexity. Chiral three-dimensional polycyclic molecules bearing contiguous stereogenic centers can be synthesized from readily available planar aromatic feedstocks. Here we report...

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Detalles Bibliográficos
Autores principales: Xia, Zi-Lei, Zheng, Chao, Xu, Ren-Qi, You, Shu-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637135/
https://www.ncbi.nlm.nih.gov/pubmed/31316064
http://dx.doi.org/10.1038/s41467-019-11109-9