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Preclinical studies of toxicity and safety of the AS-48 bacteriocin

The in vitro antimicrobial potency of the bacteriocin AS-48 is well documented, but its clinical application requires investigation, as its toxicity could be different in in vitro (haemolytic and antibacterial activity in blood and cytotoxicity towards normal human cell lines) and in vivo (e.g. mice...

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Detalles Bibliográficos
Autores principales: Cebrián, Rubén, Rodríguez-Cabezas, M. Elena, Martín-Escolano, Rubén, Rubiño, Susana, Garrido-Barros, María, Montalbán-López, Manuel, Rosales, María José, Sánchez-Moreno, Manuel, Valdivia, Eva, Martínez-Bueno, Manuel, Marín, Clotilde, Gálvez, Julio, Maqueda, Mercedes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637140/
https://www.ncbi.nlm.nih.gov/pubmed/31360546
http://dx.doi.org/10.1016/j.jare.2019.06.003