Cargando…

Preclinical studies of toxicity and safety of the AS-48 bacteriocin

The in vitro antimicrobial potency of the bacteriocin AS-48 is well documented, but its clinical application requires investigation, as its toxicity could be different in in vitro (haemolytic and antibacterial activity in blood and cytotoxicity towards normal human cell lines) and in vivo (e.g. mice...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cebrián, Rubén, Rodríguez-Cabezas, M. Elena, Martín-Escolano, Rubén, Rubiño, Susana, Garrido-Barros, María, Montalbán-López, Manuel, Rosales, María José, Sánchez-Moreno, Manuel, Valdivia, Eva, Martínez-Bueno, Manuel, Marín, Clotilde, Gálvez, Julio, Maqueda, Mercedes
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637140/ https://www.ncbi.nlm.nih.gov/pubmed/31360546 http://dx.doi.org/10.1016/j.jare.2019.06.003

Ejemplares similares

Insights into Chagas treatment based on the potential of bacteriocin AS-48
por: Martín-Escolano, Rubén, et al.
Publicado: (2019)

Control of Propionibacterium acnes by natural antimicrobial substances: Role of the bacteriocin AS-48 and lysozyme
por: Cebrián, Rubén, et al.
Publicado: (2018)

Synergy of the Bacteriocin AS-48 and Antibiotics against Uropathogenic Enterococci
por: Montalbán-López, Manuel, et al.
Publicado: (2020)

LAB Bacteriocins Controlling the Food Isolated (Drug-Resistant) Staphylococci
por: Perales-Adán, Jesús, et al.
Publicado: (2018)

Advances in the preclinical characterization of the antimicrobial peptide AS-48
por: Cebrián, Rubén, et al.
Publicado: (2023)

Analysis of the Promoters Involved in Enterocin AS-48 Expression
por: Cebrián, Rubén, et al.
Publicado: (2014)

Antimicrobial Activity of the Circular Bacteriocin AS-48 against Clinical Multidrug-Resistant Staphylococcus aureus
por: Velázquez-Suárez, Cristina, et al.
Publicado: (2021)

Autophagic-related cell death of Trypanosoma brucei induced by bacteriocin AS-48
por: Martínez-García, Marta, et al.
Publicado: (2018)

The Role of Key Amino Acids in the Antimicrobial Mechanism of a Bacteriocin Model Revealed by Molecular Simulations
por: Cruz, Víctor L., et al.
Publicado: (2021)

Determination of the effect of the bacteriocin enterocin AS-48 on the microbial loads and bacterial diversity of blueberries
por: Rodríguez López, Javier, et al.
Publicado: (2023)

An in vitro iron superoxide dismutase inhibitor decreases the parasitemia levels of Trypanosoma cruzi in BALB/c mouse model during acute phase
por: Olmo, Francisco, et al.
Publicado: (2015)

Selenium Derivatives as Promising Therapy for Chagas Disease: In Vitro and In Vivo Studies
por: Martín-Escolano, Rubén, et al.
Publicado: (2021)

An Updated View of the Trypanosoma cruzi Life Cycle: Intervention Points for an Effective Treatment
por: Martín-Escolano, Javier, et al.
Publicado: (2022)

Bacteriocins of lactic acid bacteria: extending the family
por: Alvarez-Sieiro, Patricia, et al.
Publicado: (2016)

Library of Selenocyanate and Diselenide Derivatives as In Vivo Antichagasic Compounds Targeting Trypanosoma cruzi Mitochondrion
por: Martín-Escolano, Rubén, et al.
Publicado: (2021)

Effective Tetradentate Compound Complexes against Leishmania spp. that Act on Critical Enzymatic Pathways of These Parasites
por: Urbanová, Kristína, et al.
Publicado: (2018)

Embedding Biomimetic Magnetic Nanoparticles Coupled with Peptide AS-48 into PLGA to Treat Intracellular Pathogens
por: Gaglio, Salvatore Calogero, et al.
Publicado: (2022)

BAGEL3: automated identification of genes encoding bacteriocins and (non-)bactericidal posttranslationally modified peptides
por: van Heel, Auke J., et al.
Publicado: (2013)

Outer-membrane-acting peptides and lipid II-targeting antibiotics cooperatively kill Gram-negative pathogens
por: Li, Qian, et al.
Publicado: (2021)

Enterocin Cross-Resistance Mediated by ABC Transport Systems
por: Teso-Pérez, Claudia, et al.
Publicado: (2021)

Allium-Based Phytobiotic Enhances Egg Production in Laying Hens through Microbial Composition Changes in Ileum and Cecum
por: Rabelo-Ruiz, Miguel, et al.
Publicado: (2021)

Changes in the Bacterial Diversity of Human Milk during Late Lactation Period (Weeks 21 to 48)
por: Marin-Gómez, Wendy, et al.
Publicado: (2020)

Egg Production in Poultry Farming Is Improved by Probiotic Bacteria
por: Peralta-Sánchez, Juan Manuel, et al.
Publicado: (2019)

Beneficial Shifts in the Gut Bacterial Community of Gilthead Seabream (Sparus aurata) Juveniles Supplemented with Allium-Derived Compound Propyl Propane Thiosulfonate (PTSO)
por: Rabelo-Ruiz, Miguel, et al.
Publicado: (2022)

Identification of Aryl Polyamines Derivatives as Anti-Trypanosoma cruzi Agents Targeting Iron Superoxide Dismutase †
por: Martín-Escolano, Rubén, et al.
Publicado: (2022)

Bacteriocin‐phage interaction (BaPI): Phage predation of Lactococcus in the presence of bacteriocins
por: Rendueles, Claudia, et al.
Publicado: (2022)

The Cyclic Antibacterial Peptide Enterocin AS-48: Isolation, Mode of Action, and Possible Food Applications
por: Grande Burgos, María José, et al.
Publicado: (2014)

Rationally Designed Minimal Bioactive Domains of AS-48 Bacteriocin Homologs Possess Potent Antileishmanial Properties
por: Corman, Hannah N., et al.
Publicado: (2022)

Limited communication capacity unveils strategies for human interaction
por: Miritello, Giovanna, et al.
Publicado: (2013)

Bacteriocins: An Overview of Antimicrobial, Toxicity, and Biosafety Assessment by in vivo Models
por: Benítez-Chao, Diego Francisco, et al.
Publicado: (2021)

Allium Extract Implements Weaned Piglet’s Productive Parameters by Modulating Distal Gut Microbiota
por: Rabelo-Ruiz, Miguel, et al.
Publicado: (2021)

Resistance to the Bacteriocin Lcn972 Deciphered by Genome Sequencing
por: Escobedo, Susana, et al.
Publicado: (2023)

Identification and Characterization of TALE Homeobox Genes in the Endangered Fern Vandenboschia speciosa
por: Ruiz-Estévez, Mercedes, et al.
Publicado: (2017)

De Novo Sporophyte Transcriptome Assembly and Functional Annotation in the Endangered Fern Species Vandenboschia speciosa (Willd.) G. Kunkel
por: Bakkali, Mohammed, et al.
Publicado: (2021)

Comparison between the Gametophyte and the Sporophyte Transcriptomes of the Endangered Fern Vandenboschia speciosa
por: Martín-Blázquez, Rubén, et al.
Publicado: (2023)

Treatment With High-Hydrostatic Pressure, Activated Film Packaging With Thymol Plus Enterocin AS-48, and Its Combination Modify the Bacterial Communities of Refrigerated Sea Bream (Sparus aurata) Fillets
por: Ortega Blázquez, Irene, et al.
Publicado: (2018)

Leishmanicidal Activity of Nine Novel Flavonoids from Delphinium staphisagria
por: Ramírez-Macías, Inmaculada, et al.
Publicado: (2012)

NA48/2 results and NA62 perspectives
por: Hita-Hochgesand, Manuel
Publicado: (2010)

Application of Bacteriocins and Protective Cultures in Dairy Food Preservation
por: Silva, Célia C. G., et al.
Publicado: (2018)

Lectin-Like Bacteriocins
por: Ghequire, Maarten G. K., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_8e39qli4mdosnq0v7oifqe8rlp