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Gas6 is a reciprocal regulator of mitophagy during mammalian oocyte maturation
Previously, we found that the silencing of growth arrest-specific gene 6 (Gas6) expression in oocytes impairs cytoplasmic maturation through mitochondrial overactivation with concurrent failure of pronuclear formation after fertilization. In this study, we report that Gas6 regulates mitophagy and sa...
Autores principales: | Kim, Kyeoung-Hwa, Kim, Eun-Young, Ko, Jung-Jae, Lee, Kyung-Ah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637152/ https://www.ncbi.nlm.nih.gov/pubmed/31316104 http://dx.doi.org/10.1038/s41598-019-46459-3 |
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