DRP-1 functions independently of mitochondrial structural perturbations to facilitate BH3 mimetic-mediated apoptosis

Maintenance of mitochondrial integrity is critical for normal cellular homoeostasis. Most cells respond to stress stimuli and undergo apoptosis by perturbing mitochondrial structure and function to release proteins, such as cytochrome c, which are essential for the execution of the intrinsic apoptot...

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Detalles Bibliográficos
Autores principales: Milani, Mateus, Beckett, Alison J., Al-Zebeeby, Aoula, Luo, Xu, Prior, Ian A., Cohen, Gerald M., Varadarajan, Shankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637195/
https://www.ncbi.nlm.nih.gov/pubmed/31341643
http://dx.doi.org/10.1038/s41420-019-0199-x

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