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Numerical investigation of hemodynamic performance of a stent in the main branch of a coronary artery bifurcation

[Image: see text] Introduction: The effect of a bare-metal stent on the hemodynamics in the main branch of a coronary artery bifurcation with a particular type of stenosis was numerically investigated by the computational fluid dynamics (CFD). Methods: Three-dimensional idealized geometry of bifurca...

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Autores principales: Razavi, Seyed Esmail, Farhangmehr, Vahid, Babaie, Zahra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637217/
https://www.ncbi.nlm.nih.gov/pubmed/31334041
http://dx.doi.org/10.15171/bi.2019.13
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author Razavi, Seyed Esmail
Farhangmehr, Vahid
Babaie, Zahra
author_facet Razavi, Seyed Esmail
Farhangmehr, Vahid
Babaie, Zahra
author_sort Razavi, Seyed Esmail
collection PubMed
description [Image: see text] Introduction: The effect of a bare-metal stent on the hemodynamics in the main branch of a coronary artery bifurcation with a particular type of stenosis was numerically investigated by the computational fluid dynamics (CFD). Methods: Three-dimensional idealized geometry of bifurcation was constructed in Catia modelling commercial software package. The Newtonian blood flow was assumed to be incompressible and laminar. CFD was utilized to calculate the shear stress and blood pressure distributions on the wall of main branch. In order to do the numerical simulations, a commercial software package named as COMSOL Multiphysics 5.3 was employed. Two types of stent , namely, one-part stent and two-part stent were applied to prevent the build-up and progression of the atherosclerotic plaques in the main branch. Results: A particular type of stenosis in the main branch was considered in this research. It occurred before and after the side branch. Moreover, it was found that the main branch with an inserted one-part stent had the smallest region with the wall shear stress (WSS) below 0.5 Pa which was the minimum WSS in the main branch without the stenosis. Conclusion: The use of a one-part stent in the main branch of a coronary artery bifurcation for the aforementioned type of stenosis is recommended.
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spelling pubmed-66372172019-07-22 Numerical investigation of hemodynamic performance of a stent in the main branch of a coronary artery bifurcation Razavi, Seyed Esmail Farhangmehr, Vahid Babaie, Zahra Bioimpacts Original Research [Image: see text] Introduction: The effect of a bare-metal stent on the hemodynamics in the main branch of a coronary artery bifurcation with a particular type of stenosis was numerically investigated by the computational fluid dynamics (CFD). Methods: Three-dimensional idealized geometry of bifurcation was constructed in Catia modelling commercial software package. The Newtonian blood flow was assumed to be incompressible and laminar. CFD was utilized to calculate the shear stress and blood pressure distributions on the wall of main branch. In order to do the numerical simulations, a commercial software package named as COMSOL Multiphysics 5.3 was employed. Two types of stent , namely, one-part stent and two-part stent were applied to prevent the build-up and progression of the atherosclerotic plaques in the main branch. Results: A particular type of stenosis in the main branch was considered in this research. It occurred before and after the side branch. Moreover, it was found that the main branch with an inserted one-part stent had the smallest region with the wall shear stress (WSS) below 0.5 Pa which was the minimum WSS in the main branch without the stenosis. Conclusion: The use of a one-part stent in the main branch of a coronary artery bifurcation for the aforementioned type of stenosis is recommended. Tabriz University of Medical Sciences 2019 2019-03-08 /pmc/articles/PMC6637217/ /pubmed/31334041 http://dx.doi.org/10.15171/bi.2019.13 Text en © 2019 The Author(s) This work is published by BioImpacts as an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/). Non-commercial uses of the work are permitted, provided the original work is properly cited.
spellingShingle Original Research
Razavi, Seyed Esmail
Farhangmehr, Vahid
Babaie, Zahra
Numerical investigation of hemodynamic performance of a stent in the main branch of a coronary artery bifurcation
title Numerical investigation of hemodynamic performance of a stent in the main branch of a coronary artery bifurcation
title_full Numerical investigation of hemodynamic performance of a stent in the main branch of a coronary artery bifurcation
title_fullStr Numerical investigation of hemodynamic performance of a stent in the main branch of a coronary artery bifurcation
title_full_unstemmed Numerical investigation of hemodynamic performance of a stent in the main branch of a coronary artery bifurcation
title_short Numerical investigation of hemodynamic performance of a stent in the main branch of a coronary artery bifurcation
title_sort numerical investigation of hemodynamic performance of a stent in the main branch of a coronary artery bifurcation
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637217/
https://www.ncbi.nlm.nih.gov/pubmed/31334041
http://dx.doi.org/10.15171/bi.2019.13
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