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Combined alignments of sequences and domains characterize unknown proteins with remotely related protein search PSISearch2D

Iterative homology search has been widely used in identification of remotely related proteins. Our previous study has found that the query-seeded sequence iterative search can reduce homologous over-extension errors and greatly improve selectivity. However, iterative homology search remains challeng...

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Detalles Bibliográficos
Autores principales: Yang, Minglei, Zhang, Wenliang, Yao, Guocai, Zhang, Haiyue, Li, Weizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637259/
https://www.ncbi.nlm.nih.gov/pubmed/31317184
http://dx.doi.org/10.1093/database/baz092