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Non-tuberculous mycobacterial ocular infection masquerading as choroidal tumour – a diagnostic conundrum
Purpose: To report a rare case of non-tuberculous mycobacterial (NTM) choroiditis masquerading as choroidal tumour, where the initial diagnosis was masked by keratitis. Case description: A 57-year-old heroin chaser with a pre-existing left eye blindness due to past blunt trauma presented with diffus...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
German Medical Science GMS Publishing House
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637434/ https://www.ncbi.nlm.nih.gov/pubmed/31355123 http://dx.doi.org/10.3205/oc000114 |
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author | Yeap, Khy Ching Sivagurunathan, Premala Devi Raman, Puspha Khalid, Khairul Husnaini Mohd |
author_facet | Yeap, Khy Ching Sivagurunathan, Premala Devi Raman, Puspha Khalid, Khairul Husnaini Mohd |
author_sort | Yeap, Khy Ching |
collection | PubMed |
description | Purpose: To report a rare case of non-tuberculous mycobacterial (NTM) choroiditis masquerading as choroidal tumour, where the initial diagnosis was masked by keratitis. Case description: A 57-year-old heroin chaser with a pre-existing left eye blindness due to past blunt trauma presented with diffuse bacterial keratitis on the same side. Systemic examination revealed multiple non-tender cervical lymphadenopathies. B-scan ultrasonography showed a hyperechoic choroidal mass with surrounding exudative retinal detachment, resembling a choroidal tumour. However, computed tomography (CT) and magnetic resonance imaging (MRI) scan findings were suggestive of inflammatory choroidal changes. Inflammatory markers were significantly raised and infective screening was positive for HIV and Hepatitis C. Tuberculosis workup was normal. In view of intractable pain, evisceration was done and his vitreous humour was sent for polymerase chain reaction (PCR). It was reported to be positive for Mycobacterium Fortuitum. Conclusion: NTM ocular infections are rare, challenging to diagnose, and potentially sight threatening. Early recognition and prompt treatment is life and vision saving. |
format | Online Article Text |
id | pubmed-6637434 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | German Medical Science GMS Publishing House |
record_format | MEDLINE/PubMed |
spelling | pubmed-66374342019-07-26 Non-tuberculous mycobacterial ocular infection masquerading as choroidal tumour – a diagnostic conundrum Yeap, Khy Ching Sivagurunathan, Premala Devi Raman, Puspha Khalid, Khairul Husnaini Mohd GMS Ophthalmol Cases Article Purpose: To report a rare case of non-tuberculous mycobacterial (NTM) choroiditis masquerading as choroidal tumour, where the initial diagnosis was masked by keratitis. Case description: A 57-year-old heroin chaser with a pre-existing left eye blindness due to past blunt trauma presented with diffuse bacterial keratitis on the same side. Systemic examination revealed multiple non-tender cervical lymphadenopathies. B-scan ultrasonography showed a hyperechoic choroidal mass with surrounding exudative retinal detachment, resembling a choroidal tumour. However, computed tomography (CT) and magnetic resonance imaging (MRI) scan findings were suggestive of inflammatory choroidal changes. Inflammatory markers were significantly raised and infective screening was positive for HIV and Hepatitis C. Tuberculosis workup was normal. In view of intractable pain, evisceration was done and his vitreous humour was sent for polymerase chain reaction (PCR). It was reported to be positive for Mycobacterium Fortuitum. Conclusion: NTM ocular infections are rare, challenging to diagnose, and potentially sight threatening. Early recognition and prompt treatment is life and vision saving. German Medical Science GMS Publishing House 2019-07-05 /pmc/articles/PMC6637434/ /pubmed/31355123 http://dx.doi.org/10.3205/oc000114 Text en Copyright © 2019 Yeap et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. See license information at http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Yeap, Khy Ching Sivagurunathan, Premala Devi Raman, Puspha Khalid, Khairul Husnaini Mohd Non-tuberculous mycobacterial ocular infection masquerading as choroidal tumour – a diagnostic conundrum |
title | Non-tuberculous mycobacterial ocular infection masquerading as choroidal tumour – a diagnostic conundrum |
title_full | Non-tuberculous mycobacterial ocular infection masquerading as choroidal tumour – a diagnostic conundrum |
title_fullStr | Non-tuberculous mycobacterial ocular infection masquerading as choroidal tumour – a diagnostic conundrum |
title_full_unstemmed | Non-tuberculous mycobacterial ocular infection masquerading as choroidal tumour – a diagnostic conundrum |
title_short | Non-tuberculous mycobacterial ocular infection masquerading as choroidal tumour – a diagnostic conundrum |
title_sort | non-tuberculous mycobacterial ocular infection masquerading as choroidal tumour – a diagnostic conundrum |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637434/ https://www.ncbi.nlm.nih.gov/pubmed/31355123 http://dx.doi.org/10.3205/oc000114 |
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