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Non-tuberculous mycobacterial ocular infection masquerading as choroidal tumour – a diagnostic conundrum

Purpose: To report a rare case of non-tuberculous mycobacterial (NTM) choroiditis masquerading as choroidal tumour, where the initial diagnosis was masked by keratitis. Case description: A 57-year-old heroin chaser with a pre-existing left eye blindness due to past blunt trauma presented with diffus...

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Autores principales: Yeap, Khy Ching, Sivagurunathan, Premala Devi, Raman, Puspha, Khalid, Khairul Husnaini Mohd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: German Medical Science GMS Publishing House 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637434/
https://www.ncbi.nlm.nih.gov/pubmed/31355123
http://dx.doi.org/10.3205/oc000114
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author Yeap, Khy Ching
Sivagurunathan, Premala Devi
Raman, Puspha
Khalid, Khairul Husnaini Mohd
author_facet Yeap, Khy Ching
Sivagurunathan, Premala Devi
Raman, Puspha
Khalid, Khairul Husnaini Mohd
author_sort Yeap, Khy Ching
collection PubMed
description Purpose: To report a rare case of non-tuberculous mycobacterial (NTM) choroiditis masquerading as choroidal tumour, where the initial diagnosis was masked by keratitis. Case description: A 57-year-old heroin chaser with a pre-existing left eye blindness due to past blunt trauma presented with diffuse bacterial keratitis on the same side. Systemic examination revealed multiple non-tender cervical lymphadenopathies. B-scan ultrasonography showed a hyperechoic choroidal mass with surrounding exudative retinal detachment, resembling a choroidal tumour. However, computed tomography (CT) and magnetic resonance imaging (MRI) scan findings were suggestive of inflammatory choroidal changes. Inflammatory markers were significantly raised and infective screening was positive for HIV and Hepatitis C. Tuberculosis workup was normal. In view of intractable pain, evisceration was done and his vitreous humour was sent for polymerase chain reaction (PCR). It was reported to be positive for Mycobacterium Fortuitum. Conclusion: NTM ocular infections are rare, challenging to diagnose, and potentially sight threatening. Early recognition and prompt treatment is life and vision saving.
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spelling pubmed-66374342019-07-26 Non-tuberculous mycobacterial ocular infection masquerading as choroidal tumour – a diagnostic conundrum Yeap, Khy Ching Sivagurunathan, Premala Devi Raman, Puspha Khalid, Khairul Husnaini Mohd GMS Ophthalmol Cases Article Purpose: To report a rare case of non-tuberculous mycobacterial (NTM) choroiditis masquerading as choroidal tumour, where the initial diagnosis was masked by keratitis. Case description: A 57-year-old heroin chaser with a pre-existing left eye blindness due to past blunt trauma presented with diffuse bacterial keratitis on the same side. Systemic examination revealed multiple non-tender cervical lymphadenopathies. B-scan ultrasonography showed a hyperechoic choroidal mass with surrounding exudative retinal detachment, resembling a choroidal tumour. However, computed tomography (CT) and magnetic resonance imaging (MRI) scan findings were suggestive of inflammatory choroidal changes. Inflammatory markers were significantly raised and infective screening was positive for HIV and Hepatitis C. Tuberculosis workup was normal. In view of intractable pain, evisceration was done and his vitreous humour was sent for polymerase chain reaction (PCR). It was reported to be positive for Mycobacterium Fortuitum. Conclusion: NTM ocular infections are rare, challenging to diagnose, and potentially sight threatening. Early recognition and prompt treatment is life and vision saving. German Medical Science GMS Publishing House 2019-07-05 /pmc/articles/PMC6637434/ /pubmed/31355123 http://dx.doi.org/10.3205/oc000114 Text en Copyright © 2019 Yeap et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. See license information at http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Yeap, Khy Ching
Sivagurunathan, Premala Devi
Raman, Puspha
Khalid, Khairul Husnaini Mohd
Non-tuberculous mycobacterial ocular infection masquerading as choroidal tumour – a diagnostic conundrum
title Non-tuberculous mycobacterial ocular infection masquerading as choroidal tumour – a diagnostic conundrum
title_full Non-tuberculous mycobacterial ocular infection masquerading as choroidal tumour – a diagnostic conundrum
title_fullStr Non-tuberculous mycobacterial ocular infection masquerading as choroidal tumour – a diagnostic conundrum
title_full_unstemmed Non-tuberculous mycobacterial ocular infection masquerading as choroidal tumour – a diagnostic conundrum
title_short Non-tuberculous mycobacterial ocular infection masquerading as choroidal tumour – a diagnostic conundrum
title_sort non-tuberculous mycobacterial ocular infection masquerading as choroidal tumour – a diagnostic conundrum
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637434/
https://www.ncbi.nlm.nih.gov/pubmed/31355123
http://dx.doi.org/10.3205/oc000114
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