Identification of undecylenic acid as EAG channel inhibitor using surface plasmon resonance-based screen of KCNH channels

BACKGROUND: KCNH family of potassium channels is responsible for diverse physiological functions ranging from the regulation of neuronal excitability and cardiac contraction to the regulation of cancer progression. KCNH channels contain a Per-Arn-Sim (PAS) domain in their N-terminal and cyclic nucle...

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Detalles Bibliográficos
Autores principales: Wang, Ze-Jun, Tiwari, Purushottam B., Üren, Aykut, Brelidze, Tinatin I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637479/
https://www.ncbi.nlm.nih.gov/pubmed/31315662
http://dx.doi.org/10.1186/s40360-019-0324-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637479/
https://www.ncbi.nlm.nih.gov/pubmed/31315662
http://dx.doi.org/10.1186/s40360-019-0324-8

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